Protein Alignment CG18233 and P4ha1

DIOPT Version :9

• Sequence 1: NP_649044.3
• Gene: CG18233 / 40025
• FlyBaseID: FBgn0036795
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001303300.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 554
• Identity: 164/554 - (29%)
• Similarity: 267/554 - (48%)
• Gaps: 70/554 - (12%)

  Fly     1 MLNVVRAAAVLILVQSIHSTDPNDFLNRKYYSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDN 65
            |:.||...|:| |.||:  ..|..|       :|:..:..|:..|::.:.:...|....::|::.
Mouse     1 MIWVVLMMAIL-LPQSL--AHPGFF-------TSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQ 55

  Fly    66 LNIFLDALKRPNHKTHNEREKFVSNPLNAFGLIRRLNQDWPKLQNYTQKPLG---LEQLTAMQDI 127
            :..:.:.|.|.......:.|.||.:|:|||.|::|||.:|.:|:|...|.:.   :..||..:..
Mouse    56 IKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQY 120

  Fly   128 VSAAPESFDMNEKLKAMHRIETTYDLQPKDIAKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKR 192
            .   |...|.....||:.|::.||:|....|:||.|...:....|...||..|....:...::..
Mouse   121 F---PNDEDQVGAAKALFRLQDTYNLDTNTISKGNLPGVQHKSFLTAEDCFELGKVAYTEADYYH 182

  Fly   193 SLLWFQEALKLSTDGSLEIMNRLKEIELKGFATAVAKRSIYLSNQG-------LTNETIDDMANS 250
            :.||.::||....:|.|..::::..::...:|       :|  .||       ||.:.::.....
Mouse   183 TELWMEQALTQLEEGELSTVDKVSVLDYLSYA-------VY--QQGDLDKALLLTKKLLELDPEH 238

  Fly   251 QLQDAKLMDLEQLISSEL---KQWIND--DSTTPPTDHNLG-------------CRG----LFPK 293
            |..:..|:..|.::|.|.   |....|  |..|.|....:.             |||    :.|:
Mouse   239 QRANGNLVYFEYIMSKEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPR 303

  Fly   294 K-SNLVCRY-NSSTNAFLKLAPLKMEEISRDPYIVMFHEVISDKDIEEMKGEITEMENGWTSLGD 356
            : ..|.||| :.:.|....|||.|.|:....|.|:.||::|||.:||.:| ::.:......::.|
Mouse   304 RQKRLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVK-DLAKPRLSRATVHD 367

  Fly   357 PK--EIVSRVYWIRKESSFS-------KRINQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDF 412
            |:  ::.:..|.:.|.:..|       .|||.||.|:||..:.....:|:||:||||.::||:||
Mouse   368 PETGKLTTAQYRVSKSAWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDF 432

  Fly   413 YTDRLKEVDVNNTL--GDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPD 475
              .|..|.|....|  |:||.:.:||..:||.||.||||::..:|.||||.|:||:|.|.....|
Mouse   433 --ARKDEPDAFRELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGD 495

  Fly   476 PRSLHSVCPVLVGSRWTITKWLHYAPQLFVKPCS 509
            ..:.|:.||||||::|...||||...|.|.:||:
Mouse   496 YSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..163	CDD:285528	35/131 (27%)
		ATP-synt_B	<198..278	CDD:304375	18/91 (20%)
		P4Hc	333..498	CDD:214780	67/175 (38%)
P4ha1	NP_001303300.1	P4Ha_N	24..153	CDD:285528	35/131 (27%)
		TPR	205..238		6/41 (15%)
		P4Hc	345..518	CDD:214780	67/175 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3137
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.870