DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18233 and LOC100492280

DIOPT Version :9

Sequence 1:	NP_649044.3	Gene:	CG18233 / 40025	FlyBaseID:	FBgn0036795	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_031761347.1	Gene:	LOC100492280 / 100492280	-ID:	-	Length:	552	Species:	Xenopus tropicalis

Alignment Length:	549	Identity:	149/549 - (27%)
Similarity:	251/549 - (45%)	Gaps:	91/549 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 YSSSVLGLVKLLKMEQEFMVNFSIYANILQEKVDNLNIFLDALKRPNHKTHNEREKFVSNPLNAF 95
            :.:|:..:..||..|::.:.:...|....::|:..:..:.|.|.........:.|.|:.:|:|||
Frog    20 FFTSIGHMTDLLNTEKDLVTSLKDYIKAEEQKLAQIKKWADKLDHLTDTATKDPEGFLGHPVNAF 84

  Fly    96 GLIRRLNQDWPKLQNYTQKPLG---LEQLTAMQDIVSAAPESFDMNEKLKAMHRIETTYDLQPKD 157
            .|::|||.:|.||:|...|.:.   :..||..:...   |...|.....||:.|::.||:|....
Frog    85 KLMKRLNTEWVKLENLILKDISDGFISNLTIQRQYF---PNDEDQTGAAKALLRLQDTYNLDTDT 146

  Fly   158 IAKGLLQRTEFNYRLLFRDCLALAYHKFEIGEFKRSLLWFQEALKLSTDGSLEIMNRLKEIELKG 222
            |:||.|...:....|...||..|....:...::..:.||.::||.....|....::::..::...
Frog   147 ISKGNLPGVKHKTSLTAEDCFDLGKTAYTDADYYHTELWMEQALSQLDAGEESSLDKVMVLDYLS 211

  Fly   223 FATAVAKRSIYLSNQG-------LTNETIDDMANSQLQDAKLMDLEQLISSELKQWINDDSTTPP 280
            :|       :|  .||       ||...::.....|..:..|...|.::|.|    .|..|::|.
Frog   212 YA-------VY--QQGDLDKALTLTKLLLELDPEHQRGNGNLRYFEYIMSKE----SNKSSSSPS 263

  Fly   281 TDHNLG-------------------CRG-----LFPKKSNLVCRY-NSSTNAFLKLAPLKMEEIS 320
            ....||                   |||     ...::..|.||| :.:.:..|.|:|.|.|:..
Frog   264 EGAELGTRKGRPKDHLPERQKYEKLCRGEGVKMTSRRQKRLFCRYFDGNKDPLLILSPTKQEDEW 328

  Fly   321 RDPYIVMFHEVISDKDIEEMKGEITE-------MENGWT---------------SLGDPKE---- 359
            ..|.||.:|::|||::|.::| |:.:       :.|..|               ::.||:.
Frog   329 DKPRIVRYHDIISDEEISKVK-ELAKPRLRRATISNPITGVLETAQYRISKRRATVHDPQTGKLT 392

  Fly   360 ----IVSRVYWIRK-ESSFSKRINQRISDMTGFKLEEFPAIQLANFGVGGYFKPHYDF----YTD 415
                .||:..|:.. |.....|:|:||..:||..:.....:|:||:|:||.::||:||    ..|
Frog   393 TAQYRVSKSAWLSAYEDPVVARLNRRIEGVTGLDMSTAEELQVANYGMGGQYEPHFDFARKDEPD 457

  Fly   416 RLKEVDVNNTLGDRIGSIIFYAGEVSQGGQTVFPDLKVAVEPKKGNALFWFNAFDDSTPDPRSLH 480
            ..||:..    |:|:.:.:||..:|..||.||||::..||.||||.|:||:|.|:....|..:.|
Frog   458 AFKELGT----GNRVATWLFYMSDVEAGGATVFPEVGAAVYPKKGTAVFWYNLFESGEGDYSTRH 518

  Fly   481 SVCPVLVGSRWTITKWLHYAPQLFVKPCS 509
            :.||||||::|...||:|...|.|.:||:
Frog   519 AACPVLVGNKWVSNKWIHERGQEFRRPCN 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18233	NP_649044.3	P4Ha_N	34..163	CDD:285528	36/131 (27%)
		ATP-synt_B	<198..278	CDD:304375	16/86 (19%)
		P4Hc	333..498	CDD:214780	65/199 (33%)
LOC100492280	XP_031761347.1	P4Ha_N	24..111	CDD:400573	22/86 (26%)
LOC100492280	XP_031761347.1	P4Hc	341..536	CDD:214780	65/199 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010