DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18234 and Y43F8B.19

DIOPT Version :9

Sequence 1:	NP_649043.3	Gene:	CG18234 / 40024	FlyBaseID:	FBgn0265268	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001123044.2	Gene:	Y43F8B.19 / 6418801	WormBaseID:	WBGene00077688	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	224	Identity:	52/224 - (23%)
Similarity:	88/224 - (39%)	Gaps:	32/224 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 QHLSCHYEKNTSEFLR-IAPLKVETLSLKPHIVLYHDVIYDSEISKVKNISLPSLKSPLRILYAI 351
            :|..|.      |:|: ...:|||.::.:|.:|:|.|:....::.....: :..||...:::...
Worm     8 KHAVCF------EYLQNFQIVKVEVVAWRPGLVIYRDLFTGKQVRDHLEL-MEHLKFEEQLVVND 65

  Fly   352 DYNLKFAKIR---------EDHQSPLSLRIKDMTGEDVQEDTDFQID------NYGICGFRNFHT 401
            |.|...:|||         |||  |.:..|.| |.:::..:.:|:..      :|...|....|.
Worm    66 DGNDIVSKIRRANGTQVFHEDH--PAARSIWD-TAKNLLPNLNFKTAEDILALSYNPGGHYAAHH 127

  Fly   402 DNI------ELQDQTAELGDRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNLDHRMQ 460
            |.:      |..:.....|:|..:::........|||..||.|...:..:.|.|..|.|.....:
Worm   128 DYLLYPSEKEWDEWMRVNGNRFGTLIMAFGAAESGGATVFPRLGAAVRTKPGDAFFWFNAMGNSE 192

  Fly   461 PNQDLLHVSCPVVVGSKWTLVKWLHERPQ 489
            ......|..||:..|.|.....||..|.|
Worm   193 QEDLSEHAGCPIYKGQKQISTIWLRMRDQ 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528
CG18234	NP_649043.3	P4Hc	<371..485	CDD:214780	27/125 (22%)
Y43F8B.19	NP_001123044.2	P4Hc	43..217	CDD:214780	38/177 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810