DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18234 and CG18231

DIOPT Version :9

Sequence 1:	NP_649043.3	Gene:	CG18234 / 40024	FlyBaseID:	FBgn0265268	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_649045.2	Gene:	CG18231 / 40026	FlyBaseID:	FBgn0036796	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	141/521 - (27%)
Similarity:	250/521 - (47%)	Gaps:	101/521 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ITNSAM--SIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAH 83
            :.|:::  ||..:.:|:::|..||:.:::||..|..|:..:::.:..|..:.:.|..:.|::|.:
  Fly    11 VENNSVYSSITRLLKLLEMEEIFITNIKAYTNKLAEKVKNLQAYIDSVDYEFQQSFEDREKYVGN 75

  Fly    84 PLNAFSLIRRLHEDWTQAELLMLNQVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQ 148
            |:|||||:||.|:|..:........||:|.|.|:|..:.:. |...|:..::|.:..::|.|:|:
  Fly    76 PINAFSLVRRTHQDLPKWHNYSQQIVGMEELFALEEIIAKV-PDKKDMAYSLGEMHRIEQIYDLE 139

  Fly   149 PSDIANGLLMGQQYNASLTTLNCQALANACMNFNYDKY--ALNWFKAAVDHYNDDRDGQVYREVF 211
            ..::|.|.:.|:||:...:..:|.||..  ..|..:.|  |..||:.|:.| ..:.:.::...:.
  Fly   140 AIELARGRIQGKQYDFRPSIRDCVALGE--HKFKREDYQRASMWFRVAIKH-EPEGNAEIINSIL 201

  Fly   212 DFRLPDLYINYTSVLVTKGF------------RKAAWKVLQ--DVADLDATL--WLLRKD---IY 257
            .....:||..|...::..|.            :|.:::.|.  .:||:.:.|  .|.:.|   :|
  Fly   202 GDPKVNLYTLYAKSMLIFGMIKSNPSMTIAEAKKISYEALNKASLADIKSLLNELLSQTDDEIVY 266

  Fly   258 E--VGKIDVPDPTFIITPWFDVTGCLRVGQ---TSQHLSCHYEKNTSEFLRIAPLKVETLSLKPH 317
            |  |.|....|        ::: ||.  ||   ...|: |.|....:|||::||||.|.|:..|:
  Fly   267 EMNVNKTKPSD--------YEI-GCR--GQFLRRRNHV-CTYNFTITEFLKLAPLKQEVLNWDPY 319

  Fly   318 IVLYHDVIYDSEISKVKNISLPSLKSPLRILYAIDYNLKFAKIREDHQSPLSLRIKDMTGEDVQE 382
            ||:||||:.|.||.|:||        .|....|::.|            |:..||    .:.:.|
  Fly   320 IVIYHDVLNDDEIDKLKN--------HLNDTDAVEVN------------PIEKRI----FQRINE 360

  Fly   383 DTDFQIDNYGICGFRNFHTDNIELQDQTAELGDRL---------TSIMFFMNDVAQGGALAFPNL 438
            .|....:          |:|    |...::.|.|.         .:::||:|:|..|||:.||.|
  Fly   361 LTRLSFE----------HSD----QQIVSKNGPRTHKHKKEYLKGTLLFFLNNVELGGAMVFPKL 411

  Fly   439 NLTIWPQKGSALVWRN-LDHRMQPNQDLLHVSCPVVVGSKWTLVK--WLHERPQMFSRPCTTGRK 500
            .::::|||||.|.|.| ||.|.:|      :.|||:.|:|..:.:  ..:.||..:.: ..:.:|
  Fly   412 KISVFPQKGSCLFWHNTLDPRSEP------LECPVLQGNKRVITQKGAYNGRPMQYKK-AKSNQK 469

  Fly   501 F 501
            |
  Fly   470 F 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528	38/129 (29%)
CG18234	NP_649043.3	P4Hc	<371..485	CDD:214780	36/125 (29%)
CG18231	NP_649045.2	P4Ha_N	19..148	CDD:285528	38/129 (29%)
CG18231	NP_649045.2	2OG-FeII_Oxy	322..449	CDD:304390	50/170 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461935
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900