Protein Alignment CG18234 and PH4alphaSG1

DIOPT Version :10

• Sequence 1: NP_649043.3
• Gene: CG18234 / 40024
• FlyBaseID: FBgn0265268
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_733376.1
• Gene: PH4alphaSG1 / 326112
• FlyBaseID: FBgn0051014
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 149/562 - (26%)
• Similarity: 247/562 - (43%)
• Gaps: 111/562 - (19%)

  Fly     3 IILSICLISLGPPIGLCEITNSAMSIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQ 67
            ||||  |:.:.|..|     :...:|:.::.|:|:|.|.:.:.:.|....:.:.:.::..|.::.
  Fly     6 IILS--LLCVFPVNG-----DYYSAISELERLLDVEAFIVEKFDEYLERAQQEQENLKRFLDQID 63

  Fly    68 SKREISRRNPEEFVAHPLNAFSLIRRLHEDWTQAELLMLNQV-GLEHLQAIETGLEEA------- 124
            .::. .|.:.||:..:|:|||..|:||..||   :..:.:.| ...:.:..:..|.::
  Fly    64 EQQN-DRGDLEEYFGNPINAFITIKRLVHDW---KFNVFDPVFDSSNFETYKNNLSDSLEKINFK 124

  Fly   125 QPSDNDLNDAIGGIISLQQFYNLQPSDIANGLLMGQQYNA---SLTTLNCQALA-NACMNFNYDK 185
            .|:..||:.|...::.||..|.|....:|:|:|...:.||   ||:..:|..|. |.|....| .
  Fly   125 GPTQEDLHGATRALLRLQNMYQLNTDHLASGVLHPGEKNALGTSLSASDCFELGKNLCEIKEY-S 188

  Fly   186 YALNWFKAAVDHYNDDRDGQVYREVFDFRLPDLYINYTSVLVTKGFRKAAWKVLQDVADL--DAT 248
            |...|...|....:....|.:...|.|..:.:   :.:|.....|..|.|:|:..::.|.  |..
  Fly   189 YGSEWLLEARKRLHGKPLGFISPNVSDVEILE---HLSSAFNGLGNLKLAYKLNNEILDKKPDHE 250

  Fly   249 LWLLRKDIYEVG------------KIDVPDPTFIITPWFDVTGCLRVGQTSQ------------- 288
            ..|..|.:|| |            ::::|                ::.:..|
  Fly   251 EALKNKILYE-GQLARERSFAPRKQVELP----------------QIAEKEQKESYKLYTQVCRG 298

  Fly   289 --HLSCHYEKNTS--------EFLRIAPLKVETLSLKPHIVLYHDVIYDSEI------------- 330
              |.|...::|..        .:.|::|.|:|.|::.|::...|:|::||||
  Fly   299 ELHQSPREQRNLRCWLYHQGVPYYRLSPFKIEQLNVDPYVAYVHEVLWDSEIDTIMEHGKGNMER 363

  Fly   331 SKVKNISLPSLKSPLRI-----LYAIDYNLKFAKIREDHQSPLSLRIKDMTGEDVQEDTDFQIDN 390
            |||.. |..|..|.:||     |: .|.|...:||::        |::|:||...:.....|:.|
  Fly   364 SKVGQ-SENSTTSEVRISRNTWLW-YDANPWLSKIKQ--------RLEDVTGLSTESAEPLQLVN 418

  Fly   391 YGICGFRNFHTDNIELQDQT--AELGDRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWR 453
            |||.|....|.|.:|...|:  :..|:||.:.:|::||||.|||.|||.|.|.:.|.|||.|:|.
  Fly   419 YGIGGQYEPHFDFVEDDGQSVFSWKGNRLLTALFYLNDVALGGATAFPFLRLAVPPVKGSLLIWY 483

  Fly   454 NLDHRMQPNQDLLHVSCPVVVGSKWTLVKWLHERPQMFSRPC 495
            ||......:....|..|||:.||||...:|.|...|.|.|||
  Fly   484 NLHSSTHKDFRTKHAGCPVLQGSKWICNEWFHVGAQEFRRPC 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..159	CDD:462433	32/139 (23%)
		P4Hc	<371..485	CDD:214780	47/115 (41%)
PH4alphaSG1	NP_733376.1	P4Ha_N	23..159	CDD:462433	32/139 (23%)
		P4Hc	347..515	CDD:214780	64/177 (36%)