Protein Alignment CG18234 and P4ha3

DIOPT Version :10

• Sequence 1: NP_649043.3
• Gene: CG18234 / 40024
• FlyBaseID: FBgn0265268
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: XP_006508007.1
• Gene: P4ha3 / 320452
• MGIID: 2444049
• Length: 551
• Species: Mus musculus
• Alignment Length: 559
• Identity: 142/559 - (25%)
• Similarity: 229/559 - (40%)
• Gaps: 125/559 - (22%)

  Fly    21 ITNSAMSIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPL 85
            :|:.|.::|..:.|:.....::...|:....|....|.:.||.::::..           |.:||
Mouse    32 LTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIP-----------VVNPL 85

  Fly    86 NAFSLIRRLHEDWTQAELLMLNQVGLEHLQAIETGLEEAQ---PSDNDLNDAIGGIISLQQFYNL 147
            .||:||:||..||..   ::.:....|:::|::.|.|:.:   |:..||..|...::.||..|.|
Mouse    86 LAFTLIKRLQSDWRN---VVHSLEATENIRALKDGYEKVEQDLPAFEDLEGAARALMRLQDVYML 147

  Fly   148 QPSDIANGL-----------LMGQQYNASLTTLNC-QALANAC----MNFNYDK----YALNWFK 192
            ....:|.|:           |...:...|||..:| |....:|    :...||.    :|:.|.:
Mouse   148 NVKGLARGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKPSCGSRSLQVAYDTGDYYHAIPWLE 212

  Fly   193 AAVDHYN------DDRDGQVYREVFDF-----------------------------RLPDLYINY 222
            .||..:.      ...|.....:..|:                             |:....:.|
Mouse   213 EAVSLFRRAHGEWKTEDEASLEDALDYLAFACFQVGNVSCALSLSREFLVYSPDNKRMARNVLKY 277

  Fly   223 TSVLVTKGFRKAAWKVLQ--DVADLDATLWLLRKDIYEVGKIDVPDPTFIITPWFDVTG-CLRVG 284
            ..:|...|.:.||...:|  :|..|..      :|.||                    | |..:|
Mouse   278 ERLLAENGHQMAAETAIQRPNVPHLQT------RDTYE--------------------GLCQTLG 316

  Fly   285 QTSQH-----LSCHYEKNTSEFLRIAPLKVETLSLKPHIVLYHDVIYDSEISKVKNISLPSLKSP 344
            ....|     |.|.||.|:|.:|.:.|.:.|.:.|:|.|.||||.:.|.|..|::.::.|.|:
Mouse   317 SQPTHYQIPSLYCSYETNSSPYLLLQPARKEVVHLRPLIALYHDFVSDEEAQKIRELAEPWLQ-- 379

  Fly   345 LRILYA-------IDYNLKFAKIREDHQSP----LSLRIKDMTGEDVQED--TDFQIDNYGICGF 396
             |.:.|       ::|.:..:...:|...|    |..||..:||.|:|..  ...|:.||||.|.
Mouse   380 -RSVVASGEKQLQVEYRISKSAWLKDTVDPMLVTLDHRIAALTGLDIQPPYAEYLQVVNYGIGGH 443

  Fly   397 RNFHTDNIELQDQ---TAELGDRLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNLDHR 458
            ...|.|:......   ..:.|:|:.:.|.:::.|..|||.||...|.::...|.:||.|.||...
Mouse   444 YEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRS 508

  Fly   459 MQPNQDLLHVSCPVVVGSKWTLVKWLHERPQMFSRPCTT 497
            .:.:.|.||..|||:||.||...||:||..|.|.|||:|
Mouse   509 GEGDGDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCST 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..159	CDD:462433	33/145 (23%)
		P4Hc	<371..485	CDD:214780	42/118 (36%)
P4ha3	XP_006508007.1	P4Ha_N	31..158	CDD:462433	34/139 (24%)
		P4Hc	363..535	CDD:214780	53/174 (30%)