DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18234 and phy-4

DIOPT Version :9

Sequence 1:	NP_649043.3	Gene:	CG18234 / 40024	FlyBaseID:	FBgn0265268	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_001123049.1	Gene:	phy-4 / 189869	WormBaseID:	WBGene00012815	Length:	282	Species:	Caenorhabditis elegans

Alignment Length:	269	Identity:	69/269 - (25%)
Similarity:	120/269 - (44%)	Gaps:	63/269 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   268 TFI---ITPWFDVT---------GC---LRVGQTSQ--HLSCHYEKNTSEFLRIAPLKVETLSLK 315
            |:|   :||:.|.|         .|   || |.:|:  .|.| |..:....:|    |||.||.:
Worm    12 TYIFNFLTPFTDETLEFNDKIWDKCGKELR-GDSSRDGRLVC-YRLHKHLLIR----KVEILSSE 70

  Fly   316 PHIVLYHDVIY---------DSEISKVKNISLPSL-----KSPLR------ILYAIDYNLKFAKI 360
            |.|:.||:.::         ::|..:::.:.:...     ||.:|      :::.  ....||:|
Worm    71 PFILQYHNQVHRRLAKRAVQEAEALRLEQLKISGFTTTPEKSQVRAANGTWLIHT--GRPSFARI 133

  Fly   361 REDHQSPLSLRIKDMTGEDVQEDTDFQIDNYGICGFRNFHTD------NIELQDQTAELGDRLTS 419
            .|..|:       ::...|:.....:||.:|...|:...|.|      |::|.:..   |:|:.:
Worm   134 FEGLQA-------NINSLDLSTAEPWQILSYNADGYYAPHYDYLNPATNVQLVEGR---GNRIAT 188

  Fly   420 IMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNLDHRMQPNQDLLHVSCPVVVGSKWTLVKWL 484
            ::..:....:||...||.|||.|.|:.|..:||.|.....:.|...||.:||:..|:|.....|:
Worm   189 VLVILQIAKKGGTTVFPRLNLNIRPKAGDVIVWLNTLSTGESNSQTLHAACPIHEGTKIGATLWV 253

  Fly   485 HERPQMFSR 493
            ||:  :||:
Worm   254 HEK--IFSQ 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528
CG18234	NP_649043.3	P4Hc	<371..485	CDD:214780	32/119 (27%)
phy-4	NP_001123049.1	P4Hc	81..254	CDD:214780	41/184 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910