DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18234 and phy-3

DIOPT Version :9

Sequence 1:	NP_649043.3	Gene:	CG18234 / 40024	FlyBaseID:	FBgn0265268	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	NP_507251.2	Gene:	phy-3 / 188624	WormBaseID:	WBGene00004026	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	303	Identity:	61/303 - (20%)
Similarity:	118/303 - (38%)	Gaps:	71/303 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 LVTKGFRKAAWKVLQDVADLDAT--------LWLLRKDIYEVGKIDVPDPTFIITPWFDVTGCLR 282
            :::..||    ::|..|:.|.||        :|||.:|.:     :.....|:...|:
Worm     1 MISVTFR----QILGLVSLLCATWLYSQCRHIWLLAQDDF-----NEQFTNFLGEKWW------- 49

  Fly   283 VGQTSQHLSC-------HYEKNTSEFL----RIAPLKVETLSLKPHIVLYHDVI----------- 325
              .|.|...|       .::||.|..:    .:.|:.:|.:|..|.:|:|.:::
Worm    50 --STDQLELCDDETKDTKWQKNDSICITYVYNMLPVDMEIISWAPTLVIYRNLMSPRQTASFLNF 112

  Fly   326 ---YDSEISKVKNISLPSLKSPLRILYAIDYNLKFAKIREDHQSPLSLRI---KDMTGEDVQEDT 384
               .|.||.|..:.. .|:::..|     ..|..|.. .||....:.:::   |.:.|.::....
Worm   113 IEQRDLEIQKTSDFG-TSIETTHR-----RANGSFIP-PEDSNVTVEIKMQAQKRIPGLNLTVAE 170

  Fly   385 DFQIDNYGICGFRNFHTDNIELQDQ------TAELGDRLTSIMFFMNDVAQGGALAFPNLNLTIW 443
            .|...:|...|....|.|.::.:.:      ..:.|:|:.:::|.:....:||...||::..|:.
Worm   171 HFSALSYLPGGHYAVHYDYLDYRSKQDYDWWMNKTGNRIGTLIFVLKPAEKGGGTVFPSIGSTVR 235

  Fly   444 PQKGSALVWRNLDHRMQPNQDLL--HVSCPVVVGSKWTLVKWL 484
            ...|.|..|.|.  :....:::|  |..||:..|.|.....|:
Worm   236 ANAGDAFFWFNA--QADEEKEMLSNHGGCPIYEGRKVIATIWI 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528
CG18234	NP_649043.3	P4Hc	<371..485	CDD:214780	26/125 (21%)
phy-3	NP_507251.2	P4Hc	102..277	CDD:214780	36/184 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770