Protein Alignment CG18234 and P4ha1

DIOPT Version :10

• Sequence 1: NP_649043.3
• Gene: CG18234 / 40024
• FlyBaseID: FBgn0265268
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_035160.1
• Gene: P4ha1 / 18451
• MGIID: 97463
• Length: 534
• Species: Mus musculus
• Alignment Length: 536
• Identity: 149/536 - (27%)
• Similarity: 243/536 - (45%)
• Gaps: 96/536 - (17%)

  Fly    27 SIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPLNAFSLI 91
            ||..|.:|:..|...::.::.|..|.::|::.::...:::......:.::||.||.||:|||.|:
Mouse    24 SIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLM 88

  Fly    92 RRLHEDWTQAELLMLNQVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIANGL 156
            :||:.:|::.|.|:|..:....:..: |...:..|:|.|...|...:..||..|||..:.|:.|.
Mouse    89 KRLNTEWSELENLILKDMSDGFISNL-TIQRQYFPNDEDQVGAAKALFRLQDTYNLDTNTISKGN 152

  Fly   157 LMGQQYNASLTTLNCQALANACMNFNYDKYALN-WFKAAVDHYNDDRDGQVYR-EVFDFRLPDLY 219
            |.|.|:.:.||..:|..|...... ..|.|... |.:.|:....:.....|.: .|.|      |
Mouse   153 LPGVQHKSFLTAEDCFELGKVAYT-EADYYHTELWMEQALTQLEEGELSTVDKVSVLD------Y 210

  Fly   220 INYTSVLVTKGFRKAAWKVLQDVADLDATLWLLRKDIYEVGKIDVPDP------------TFIIT 272
            ::|.              |.|. .|||..| ||.|.:.|:      ||            .:|::
Mouse   211 LSYA--------------VYQQ-GDLDKAL-LLTKKLLEL------DPEHQRANGNLVYFEYIMS 253

  Fly   273 PWFDVTGCLRVGQTSQ-------------------------------------HLSCHY-EKNTS 299
            ...|........|:.|                                     .|.|.| :.|.:
Mouse   254 KEKDANKSASGDQSDQKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRN 318

  Fly   300 EFLRIAPLKVETLSLKPHIVLYHDVIYDSEISKVKNISLPSLK-----SPLR-ILYAIDYNLKFA 358
            ....:||.|.|....||.|:.:||:|.|:||..||:::.|.|:     :|:. .|..:.|.:..:
Mouse   319 PKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKS 383

  Fly   359 KIREDHQSP----LSLRIKDMTGEDVQEDTDFQIDNYGICGFRNFHTDNIELQDQTA--EL--GD 415
            .....::.|    :::||:|:||.||....:.|:.|||:.|....|.|.....:..|  ||  |:
Mouse   384 AWLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGN 448

  Fly   416 RLTSIMFFMNDVAQGGALAFPNLNLTIWPQKGSALVWRNLDHRMQPNQDLLHVSCPVVVGSKWTL 480
            |:.:.:|:|:||:.|||..||.:..::||:||:|:.|.||....:.:....|.:|||:||:||..
Mouse   449 RIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVS 513

  Fly   481 VKWLHERPQMFSRPCT 496
            .||||||.|.|.||||
Mouse   514 NKWLHERGQEFRRPCT 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..159	CDD:462433	37/131 (28%)
		P4Hc	<371..485	CDD:214780	46/117 (39%)
P4ha1	NP_035160.1	P4Ha_N	24..155	CDD:462433	37/131 (28%)
		TPR	205..238		16/60 (27%)
		P4Hc	345..518	CDD:214780	57/172 (33%)