Protein Alignment CG18234 and dpy-18

DIOPT Version :9

• Sequence 1: NP_649043.3
• Gene: CG18234 / 40024
• FlyBaseID: FBgn0265268
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_499464.1
• Gene: dpy-18 / 176569
• WormBaseID: WBGene00001077
• Length: 559
• Species: Caenorhabditis elegans
• Alignment Length: 532
• Identity: 148/532 - (27%)
• Similarity: 240/532 - (45%)
• Gaps: 74/532 - (13%)

  Fly    27 SIAGMKELVDLEGFFISEMESYTAALKNKIDLMESLLQEVQSKREISRRNPEEFVAHPLNAFSLI 91
            |||.|:.|::.|......::.|....:.::..::.|.:|...|.|||..|..:.:.:|:|||.||
 Worm    21 SIADMQNLLETERNIPKILDKYIHDEEERLVQLKKLSEEYSKKNEISIENGLKDITNPINAFLLI 85

  Fly    92 RRLHEDWTQAELLM-LNQVGLEHLQAIETGLEEAQPSDNDLNDAIGGIISLQQFYNLQPSDIANG 155
            :|...||.:.|..| .|:.|.......:.......|:.:||:.|..|::.||..|.|...|:|:|
 Worm    86 KRKIFDWKEIESKMNANKAGNVVSSITDDSYGVRYPTADDLSGAAIGLLRLQDTYRLDTKDLADG 150

  Fly   156 LLMGQQYNASLTTLNCQALANACMNFNYDKYALNWFKAAVDHYNDDRDGQVYREVFD------FR 214
            .:...|.|.:.:..:|..:|.|..|.:...:.:.|.:.|.....|:.:..|  ||.|      |.
 Worm   151 KIYADQGNYTFSAKDCFEIARAAYNEHDFYHTVMWMEEAQRRLGDEVEPTV--EVEDILEYLAFA 213

  Fly   215 L-------------PDLY-IN------------YTSVLVTKGFRKAAW-KVLQDVADL--DATLW 250
            |             .:|| :|            |..:|..:|.|::.. |.|..:.:.  |:.|.
 Worm   214 LYKQNNLKHALKLTEELYKMNPTHPRAKGNVKWYEDLLEQEGVRRSDMRKNLPPIQNRRPDSVLG 278

  Fly   251 LLRKDIYE-VGKIDVPDPTFIITPWFDVTGCLRVGQTS-QHLSCHYEKNTSEFLRIAPLKVETLS 313
            ...:.:|| :.:.:||                 |.|.. ..|.|:| |....||..||:|||...
 Worm   279 NTERTMYEALCRNEVP-----------------VSQKDISRLYCYY-KRDRPFLVYAPIKVEIKR 325

  Fly   314 LKPHIVLYHDVIYDSEISKVKNISLPSL------KSPLRILYAIDYNL-KFAKIRE---DHQSPL 368
            ..|..||:.|||.|.|::.::.::.|.|      .|....|....|.: |.|.::|   |....:
 Worm   326 FNPLAVLFKDVISDDEVAAIQELAKPKLARATVHDSVTGKLVTATYRISKSAWLKEWEGDVVETV 390

  Fly   369 SLRIKDMTGEDVQEDTDFQIDNYGICGFRNFHTDNIELQD----QTAELGDRLTSIMFFMNDVAQ 429
            :.||..||..:::...:.||.||||.|..:.|.|:.:.::    ::...|:|:.:::|:|:..:.
 Worm   391 NKRIGYMTNLEMETAEELQIANYGIGGHYDPHFDHAKKEESKSFESLGTGNRIATVLFYMSQPSH 455

  Fly   430 GGALAFPNLNLTIWPQKGSALVWRNLDHRMQPNQDLLHVSCPVVVGSKWTLVKWLHERPQMFSRP 494
            ||...|.....||.|.|..||.|.||..:...|.|..|.:|||:||.||...||:||:...|.||
 Worm   456 GGGTVFTEAKSTILPTKNDALFWYNLYKQGDGNPDTRHAACPVLVGIKWVSNKWIHEKGNEFRRP 520

  Fly   495 CTTGRKFKSHDQ 506
            |  |.|...:::
 Worm   521 C--GLKSSDYER 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18234	NP_649043.3	P4Ha_N	27..157	CDD:285528	39/130 (30%)
		P4Hc	<371..485	CDD:214780	41/117 (35%)
dpy-18	NP_499464.1	P4Ha_N	21..152	CDD:285528	39/130 (30%)
		P4Hc	338..511	CDD:214780	52/172 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920