Protein Alignment CG4174 and PH4alphaNE1

DIOPT Version :10

• Sequence 1: NP_730342.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: NP_733374.1
• Gene: PH4alphaNE1 / 43625
• FlyBaseID: FBgn0039780
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 125/521 - (23%)
• Similarity: 223/521 - (42%)
• Gaps: 112/521 - (21%)

  Fly    30 AISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAIRQSEELLKSTK--------------T 80
            :::|:...|:..|::. ::..|...:.|:..:..|:.|::|.|..|.|.:              |
  Fly    18 SLASDYFSSITGLEDL-LHTEQYLTRELRSKVNAIQTALQQLESELSSIEKEHTMAASDTENYLT 81

  Fly    81 SPRNLIYGYKVLRHLHNDWPQYFRLLKKDLGLEQIAVSQMLLT-------QQPTSVDFEESMGAM 138
            :|.|:   |::::.||.||    .|::   |..|:...:|...       ..|:..|.|.:..|:
  Fly    82 NPVNV---YRLMKRLHTDW----SLME---GRVQLMAEEMNFNATREYGLSYPSQEDVEGAALAL 136

  Fly   139 HRLQTVYNLDSYAMTEGFIDD-KDKNIRNWSADECLMLGLMYLFLKDYNQSENWLELAL------ 196
            .|||:.|.||...:.:|.::. |..:..:|  .:|..||.....::|||.::.||..::
  Fly   137 VRLQSTYKLDVAQVAQGILNGVKYGSDMSW--QDCFELGQQLFEMEDYNNTKVWLRESMERLRRQ 199

  Fly   197 -----YHYDDNVSPEVLKIKLWNYPNLLESLVEANKGLGHYFEAKKYANELLSINPN--HTYML- 253
                 .|......|:.:.:      |.:|:..::...||.:..|.:.:..:|..:|.  ..:.|
  Fly   200 TSHAPSHLAPTSGPDTVTL------NKMEATAKSLFQLGDFDTAFELSQRVLQFDPKRIRNWHLG 258

  Fly   254 ------------TQLPKLKHLQSNPAKLTKPKKVFQLQKEICSKRYRRKSGVLVCRYVDWT-PFL 305
                        ..|||.....|...:..|.:||.:.:.....::..|      |||.... |:.
  Fly   259 DKGTAPPEDIDDVYLPKHSDSYSLSQEFAKYEKVCRGEVHPIVRQELR------CRYSRGNHPYR 317

  Fly   306 KLAPLKMEELSMKPYISIFYGFLGQKDIEVLKNVSRPKLQR--IEHLSGNCSCKIGNLSTSLHDV 368
            .|||||:||.|:.||::.|:..|....|..|:.::.|::.|  :..|.|      |.|..|...|
  Fly   318 FLAPLKLEEHSLDPYVATFHDILSPGKISQLREMAVPRMHRSTVNPLPG------GQLKKSAFRV 376

  Fly   369 VRKV------NELILGI-------TGFPLKGNQMLEVINYGIAGNYNP-----EEPKIH-----N 410
            .:..      :..::|:       ||......:.|:|.|||:.|:|.|     .:|..:     |
  Fly   377 SKNAWLAYESHPTMVGMLRDLKDATGLDTTFCEQLQVANYGVGGHYEPHWDFFRDPNHYPAEEGN 441

  Fly   411 K-ANAFIFLSNAGKGGEIVFPSRHLKVRPRKGSMLVWENLKKSL------IYHQCPILKGNMWVA 468
            : |.|..:||...:||...||...:.|:|:.|::|.|.||.:||      .:..||:|||:.|:.
  Fly   442 RIATAIFYLSEVEQGGATAFPFLDIAVKPQLGNVLFWYNLHRSLDKDYRTKHAGCPVLKGSKWIG 506

  Fly   469 N 469
            |
  Fly   507 N 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4174	NP_730342.2	P4Ha_N	33..159	CDD:462433	34/146 (23%)
		TPR repeat	169..197	CDD:276809	8/38 (21%)
		TPR repeat	202..245	CDD:276809	7/42 (17%)
		PLN00052	311..>470	CDD:177683	55/191 (29%)
PH4alphaNE1	NP_733374.1	P4Ha_N	26..157	CDD:462433	33/141 (23%)
		P4Hc	341..511	CDD:214780	47/173 (27%)