DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4174 and CG34041

DIOPT Version :9

Sequence 1:	NP_001034031.2	Gene:	CG4174 / 40023	FlyBaseID:	FBgn0036793	Length:	473	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	80/339 - (23%)
Similarity:	141/339 - (41%)	Gaps:	72/339 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 AISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAI-------RQSEELLKSTKTSPRNLIY 87
            ::|....:::||::|..|..|::|...|:..|:.|..|:       .|.|....:..:||   :.
  Fly   258 SLSKSKVINILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLAIASSP---VA 319

  Fly    88 GYKVLRHLHNDWPQYFRLLKKDLGLEQIAVSQMLLTQQPTSVDFEESMGAMHRLQTVYNLDSYAM 152
            .|.::.|:.:||..:...|::|.|.:::|....:....||..|..|....:.::...|.:.:..:
  Fly   320 SYSLIHHMQSDWTHWQLFLQEDPGKDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMTAQDI 384

  Fly   153 TEGFI-DDKDKNIRN-----------------WSADECLMLGLMYLFLKDYNQSENWLELAL--- 196
            ..|.| ..:.|.|.:                 .|..:|:.|....:.:||||:|:.||.:|:
  Fly   385 ANGVILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSKEWLNVAISML 449

  Fly   197 --YHYDDNVSPEV---LK-----IKLWNYPNLLESLVEANKGLGHYFEAKKYANELLSINPNHTY 251
              ..|.|.:.|..   ||     :|..|:...||::..|                 |..||.:..
  Fly   450 ESSAYWDPIVPSADLYLKLAEVYVKQQNWTLALETVEFA-----------------LKSNPRNAQ 497

  Fly   252 MLTQLPKLK-HLQSNPAKLTKPKKVFQLQKEICSKRYR-RKSGVLVCRYVDW---TPFLKLAPLK 311
            ::....:|. |:...|.|  .||      ..|.:..|| ||:|.|.|.| |.   |.:..|||:|
  Fly   498 LIRMQKRLSYHILLGPPK--SPK------LNIENNDYRLRKNGSLYCFY-DTKIRTFYSLLAPIK 553

  Fly   312 MEELSMKPYISIFY 325
            .|.|.:.|.:.:::
  Fly   554 AEVLFIDPLVILYH 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4174	NP_001034031.2	P4Ha_N	33..157	CDD:285528	28/130 (22%)
		TPR repeat	169..197	CDD:276809	10/32 (31%)
		TPR repeat	202..245	CDD:276809	9/50 (18%)
		2OG-FeII_Oxy	<362..470	CDD:304390
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	29/131 (22%)
		TPR repeat	452..491	CDD:276809	11/55 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461977
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940