Protein Alignment CG4174 and P4ha3

DIOPT Version :10

• Sequence 1: NP_730342.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: XP_063123241.1
• Gene: P4ha3 / 361612
• RGDID: 735150
• Length: 584
• Species: Rattus norvegicus
• Alignment Length: 485
• Identity: 116/485 - (23%)
• Similarity: 201/485 - (41%)
• Gaps: 109/485 - (22%)

  Fly    19 EVVSAPESYDFAISSESQL-----SLLKLKETHVNNL-QSYKKVLKKHLQKIRRAIRQSEELLKS 77
            :..||..|...|::.|.:|     ..|:.:|..:.:| :.|.|||..|            |.||.
  Rat    29 DTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLH------------EDLKI 81

  Fly    78 TKTSPRNLIYGYKVLRHLHNDWPQYFRLLK--------KDLGLEQIAVSQMLLTQQPTSVDFEES 134
            ...:|   :..:.:::.|.:||......|:        || |.|:  |.|.|    |...|.|.:
  Rat    82 PVVNP---LLAFTLIKRLQSDWRNVVHSLEATENIRALKD-GYEK--VEQDL----PAFEDLEGA 136

  Fly   135 MGAMHRLQTVYNLDSYAMTEGF--------IDD--KDKNIRNWSADECLMLGLMYLFLKDYNQSE 189
            ..|:.|||.||.|:...:.:|.        |.|  ..:.:.:.:||:|..:|.:.....||..:.
  Rat   137 ARALMRLQDVYMLNVKGLAQGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAI 201

  Fly   190 NWLELAL---------YHYDDNVSPEVLKIKLWNYPNLLESLVEANKGLGHYFEAKKYANELLSI 245
            .|||.|:         :..:|..|.|          :.|:.|..|...:|:...|...:.|.|..
  Rat   202 PWLEEAVSLFRRSYGEWKTEDEASLE----------DALDYLAFACYQVGNVSCALSLSREFLVY 256

  Fly   246 NPNHTYMLTQLPKLK-------HLQSNPAKLTKPKKVFQLQ-----KEICS------KRYRRKSG 292
            :|::..|...:.|.:       ||.:....:.:| .|..||     :.:|.      ..|:..|
  Rat   257 SPDNKRMARNVLKYERLLAENGHLMAAETAIQRP-NVPHLQTRDTYEGLCQTLGSQPTHYQIPS- 319

  Fly   293 VLVCRY-VDWTPFLKLAPLKMEELSMKPYISIFYGFLGQKDIEVLKNVSRPKLQRIEHLSGNCSC 356
             |.|.| .:.:|:|.|.|.:.|.:.::|.:::::.|:..::.:.::.::.|.|||....||....
  Rat   320 -LYCSYETNSSPYLLLQPARKEVIHLRPLVALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQL 383

  Fly   357 KIG---NLSTSLHDVVRKV----NELILGITGFPLKG--NQMLEVINYGIAGNYNPE-------- 404
            ::.   :.|..|.|.|..|    :..|..:||..::.  .:.|:|:||||.|:|.|.
  Rat   384 QVEYRISKSAWLKDTVDPVLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPS 448

  Fly   405 ----EPKIHNK-ANAFIFLSNAGKGGEIVF 429
                :.|..|: |...|:||:...||...|
  Rat   449 SPLYKMKSGNRVATLMIYLSSVEAGGATAF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4174	NP_730342.2	P4Ha_N	33..159	CDD:462433	37/147 (25%)
		TPR repeat	169..197	CDD:276809	10/36 (28%)
		TPR repeat	202..245	CDD:276809	9/42 (21%)
		PLN00052	311..>470	CDD:177683	35/141 (25%)
P4ha3	XP_063123241.1	None