Protein Alignment CG4174 and P4ha2

DIOPT Version :10

• Sequence 1: NP_730342.2
• Gene: CG4174 / 40023
• FlyBaseID: FBgn0036793
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: XP_006532515.1
• Gene: P4ha2 / 18452
• MGIID: 894286
• Length: 557
• Species: Mus musculus
• Alignment Length: 525
• Identity: 130/525 - (24%)
• Similarity: 209/525 - (39%)
• Gaps: 92/525 - (17%)

  Fly    28 DFAISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAIRQSEELLKSTKTSPRNL----IYG 88
            :|..|......|:..::..|.:|:.|..|.:..|.||:....:.|.|...:...|...    :..
Mouse    24 EFFTSIGHMTDLIYAEKDLVQSLKEYILVEEAKLAKIKSWASKMEALTSRSAADPEGYLAHPVNA 88

  Fly    89 YKVLRHLHNDWPQYFRLLKKDLGLEQIAVSQMLLTQQPTSVDFEESMGAMHRLQTVYNLDSYAMT 153
            ||:::.|:.|||....|:.:|.....:|...:.....||..|...:..|:.|||..|.||...::
Mouse    89 YKLVKRLNTDWPALGDLVLQDASAGFVANLSVQRQFFPTDEDESGAARALMRLQDTYKLDPDTIS 153

  Fly   154 EGFIDDKDKNIRNWSADECLMLGLMYLFLKDYNQSENWLELALYHYDDNVSPEVLKIKLWNYPNL 218
            .|.:.. .|.....|.|:|..||.......||..:..|:|..|...|......|.|..:.:|
Mouse   154 RGELPG-TKYQAMLSVDDCFGLGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATVTKSLVLDY--- 214

  Fly   219 LESLVEANKGLGHYFEAKKYANELLSINPNH----------TYMLTQ-------------LPKLK 260
               |..|...||....|.:....|||::|:|          ..:|.:             |...:
Mouse   215 ---LSYAVFQLGDLHRAVELTRRLLSLDPSHERAGGNLRYFERLLEEERGKSLSNQTDAGLATQE 276

  Fly   261 HLQSNPAKLTKPKKVFQLQKEICS----KRYRRKSGVLVCRY--VDWTPFLKLAPLKMEELSMKP 319
            :|...|......:.|::   .:|.    |...|:...|.|||  .:..|.|.:||.|.|:....|
Mouse   277 NLYERPTDYLPERDVYE---SLCRGEGVKLTPRRQKKLFCRYHHGNRVPQLLIAPFKEEDEWDSP 338

  Fly   320 YISIFYGFLGQKDIEVLKNVSRPKLQRI---EHLSG---NCSCKIGNLSTSLHD---VVRKVNEL 375
            :|..:|..:..::||.:|.:::|||.|.   :..:|   ..|.::...|....|   ||.:||..
Mouse   339 HIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRR 403

  Fly   376 ILGITGFPLKGNQMLEVINYGIAGNYNP----------------------------EEPKIH--- 409
            :..|||..:|..::|:|.|||:.|.|.|                            |:....
Mouse   404 MQHITGLTVKTAELLQVANYGMGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYSDEQDAFKRLG 468

  Fly   410 --NKANAFI-FLSNAGKGGEIVFPSRHLKVRPRKGSMLVWENLKKS------LIYHQCPILKGNM 465
              |:...|: ::|:...||..|||.....:.|:||:.:.|.||.:|      ..:..||:|.|..
Mouse   469 TGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCK 533

  Fly   466 WVANK 470
            ||:||
Mouse   534 WVSNK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4174	NP_730342.2	P4Ha_N	33..159	CDD:462433	31/129 (24%)
		TPR repeat	169..197	CDD:276809	8/27 (30%)
		TPR repeat	202..245	CDD:276809	10/42 (24%)
		PLN00052	311..>470	CDD:177683	54/207 (26%)
P4ha2	XP_006532515.1	P4Ha_N	28..159	CDD:462433	32/130 (25%)
		P4Hc	348..541	CDD:214780	51/191 (27%)