DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4174 and P4ha1

DIOPT Version :9

Sequence 1:NP_001034031.2 Gene:CG4174 / 40023 FlyBaseID:FBgn0036793 Length:473 Species:Drosophila melanogaster
Sequence 2:NP_001303300.1 Gene:P4ha1 / 18451 MGIID:97463 Length:534 Species:Mus musculus


Alignment Length:515 Identity:130/515 - (25%)
Similarity:222/515 - (43%) Gaps:87/515 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 FAISSESQLSLLKLKETHVNNLQSYKKVLKKHLQKIRRAIRQSEELLKSTKTSPRNL----IYGY 89
            |..|......|:..::..|.:|:.|.|..:..|::|::...:.:.|..:....|...    :..:
Mouse    21 FFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAF 85

  Fly    90 KVLRHLHNDWPQYFRLLKKDL--GLEQIAVSQMLLTQQ--PTSVDFEESMGAMHRLQTVYNLDSY 150
            |:::.|:.:|.:...|:.||:  |.    :|.:.:.:|  |...|...:..|:.|||..||||:.
Mouse    86 KLMKRLNTEWSELENLILKDMSDGF----ISNLTIQRQYFPNDEDQVGAAKALFRLQDTYNLDTN 146

  Fly   151 AMTEGFIDD-KDKNIRNWSADECLMLGLMYLFLKDYNQSENWLELALYHYDDNVSPEVLKIKLWN 214
            .:::|.:.. :.|:.  .:|::|..||.:.....||..:|.|:|.||...::.....|.|:.:.:
Mouse   147 TISKGNLPGVQHKSF--LTAEDCFELGKVAYTEADYYHTELWMEQALTQLEEGELSTVDKVSVLD 209

  Fly   215 YPNLLESLVEANKGLGHYFEAKKYANELLSINPNHTYMLTQLPKLKHLQSNPA------------ 267
            |      |..|....|...:|.....:||.::|.|......|...:::.|...            
Mouse   210 Y------LSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEKDANKSASGDQSD 268

  Fly   268 KLTKPKK---------VFQLQKEICS----KRYRRKSGVLVCRYVDW--TPFLKLAPLKMEELSM 317
            :.|.|||         ..|..:.:|.    |...|:...|.|||.|.  .|...|||.|.|:...
Mouse   269 QKTAPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPKFILAPAKQEDEWD 333

  Fly   318 KPYISIFYGFLGQKDIEVLKNVSRPKLQRIE-HLSGNCSCKIGNLSTSLH-------------DV 368
            ||.|..|:..:...:||::|::::|:|.|.. |     ..:.|.|:|:.:             .|
Mouse   334 KPRIIRFHDIISDAEIEIVKDLAKPRLSRATVH-----DPETGKLTTAQYRVSKSAWLSGYEDPV 393

  Fly   369 VRKVNELILGITGFPLKGNQMLEVINYGIAGNYNP-------EEPKIHNK-------ANAFIFLS 419
            |.::|..|..:||..:...:.|:|.|||:.|.|.|       :||....:       |....::|
Mouse   394 VSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGNRIATWLFYMS 458

  Fly   420 NAGKGGEIVFPSRHLKVRPRKGSMLVWENL------KKSLIYHQCPILKGNMWVANKVLN 473
            :...||..|||.....|.|:||:.:.|.||      ..|..:..||:|.||.||:||.|:
Mouse   459 DVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLH 518

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4174NP_001034031.2 P4Ha_N 33..157 CDD:285528 29/131 (22%)
TPR repeat 169..197 CDD:276809 10/27 (37%)
TPR repeat 202..245 CDD:276809 9/42 (21%)
2OG-FeII_Oxy <362..470 CDD:304390 39/140 (28%)
P4ha1NP_001303300.1 P4Ha_N 24..153 CDD:285528 30/132 (23%)
TPR 205..238 8/38 (21%)
P4Hc 345..518 CDD:214780 50/177 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000199
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10869
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
33.010

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