Protein Alignment AstC-R1 and OPRD1

DIOPT Version :10

• Sequence 1: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_000902.3
• Gene: OPRD1 / 4985
• HGNCID: 8153
• Length: 372
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 114/339 - (33%)
• Similarity: 181/339 - (53%)
• Gaps: 38/339 - (11%)

  Fly    83 LYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVADECFLIGIPFLLYTMRICSWRFGEF 147
            ||..||.:||.||.||::.::|::||:|.|||||.|||:||......:||......:.:|.|||.
Human    55 LYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGEL 119

  Fly   148 MCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVI 212
            :|||.:.......|||...|.:||.|||||||||:.:..:||...||:::...|..::.:.:|::
Human   120 LCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIM 184

  Fly   213 LYASTVEQEDGINYSCNIMWPDAYKKHSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPK 277
            :.|.|..::..:  .|.:.:|.. ..:..|...:..|...|..|:..|...|.|::.:||||...
Human   185 VMAVTRPRDGAV--VCMLQFPSP-SWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLL 246

  Fly   278 PGTKSKEKRRAHRKVTRLVLTVISVYILCWLPHWISQV--ALIHSNPAQRDLSRLEILIFLLLG- 339
            .|  ||||.|:.|::||:||.|:..:::||.|..|..:  .|:       |:.|.:.|:...|.
Human   247 SG--SKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLV-------DIDRRDPLVVAALHL 302

  Fly   340 --ALVYSNSAVNPILYAFLSENFRKSFFKAFTCMNKQDINAQL------QLEPSVFTKQGSKKRG 396
              ||.|:||::||:|||||.|||::.|             .||      :.:||.|::  :::..
Human   303 CIALGYANSSLNPVLYAFLDENFKRCF-------------RQLCRKPCGRPDPSSFSR--AREAT 352

  Fly   397 GSKRLLTSNPQIPP 410
            ..:|:....|...|
Human   353 ARERVTACTPSDGP 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R1	NP_649040.2	7tmA_AstC_insect	78..364	CDD:320222	105/285 (37%)
		TM helix 1	79..105	CDD:320222	10/21 (48%)
		TM helix 2	112..138	CDD:320222	12/25 (48%)
		TM helix 3	149..179	CDD:320222	14/29 (48%)
		TM helix 4	191..213	CDD:320222	4/21 (19%)
		TM helix 5	241..270	CDD:320222	7/28 (25%)
		TM helix 6	287..317	CDD:320222	11/31 (35%)
		TM helix 7	332..357	CDD:320222	13/27 (48%)
OPRD1	NP_000902.3	7tmA_Delta_opioid_R	50..329	CDD:320217	105/285 (37%)
		TM helix 1	51..77	CDD:320217	10/21 (48%)
		TM helix 2	84..110	CDD:320217	12/25 (48%)
		TM helix 3	121..151	CDD:320217	14/29 (48%)
		TM helix 4	163..185	CDD:320217	4/21 (19%)
		TM helix 5	209..239	CDD:320217	7/29 (24%)
		TM helix 6	258..284	CDD:320217	9/25 (36%)
		TM helix 7	297..322	CDD:320217	12/24 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..372		6/29 (21%)