Protein Alignment AstC-R1 and Oprk1

DIOPT Version :10

• Sequence 1: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_038965287.1
• Gene: Oprk1 / 29335
• RGDID: 69426
• Length: 431
• Species: Rattus norvegicus
• Alignment Length: 392
• Identity: 130/392 - (33%)
• Similarity: 199/392 - (50%)
• Gaps: 54/392 - (13%)

  Fly     6 MMDVLQFVKGE---MTADSEA---NATNWY------NTNESLYTTELNHRWISGSSTIQPEESLY 58
            |...:|..:||   ..|.|..   |:::|:      ::|.|:           ||...|.|.:..
  Rat    52 MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSV-----------GSEDQQLEPAHI 105

  Fly    59 GTDLPTYQHCIATRNSFADLFTVVLYGFVCIIGLFGNTLVIYVVLRFSKMQTVTNIYILNLAVAD 123
            ...:|.             :.|.| |..|.::||.||:||::|::|::||:|.|||||.|||:||
  Rat   106 SPAIPV-------------IITAV-YSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALAD 156

  Fly   124 ECFLIGIPF--LLYTMRICSWRFGEFMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPR 186
            ......:||  .:|.|.  ||.||:.:||..:.......|||...|.:||.|||||||||:.:..
  Rat   157 ALVTTTMPFQSAVYLMN--SWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALD 219

  Fly   187 YRTLHIAKVVSAIAWSTSAVLMLPVILYASTVEQEDGINYSCNIMWPDAYKKHSGTTFILYTFFL 251
            :||...||:::...|..::.:.:..|:...|..:||.....|::.:||...........:..|..
  Rat   220 FRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVF 284

  Fly   252 GFATPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTRLVLTVISVYILCWLP-H-WISQ 314
            .|..|:..|:..|.|:|.:|:||....|  |:||.|..|::|:|||.|::|:|:||.| | :|..
  Rat   285 AFVIPVLIIIVCYTLMILRLKSVRLLSG--SREKDRNLRRITKLVLVVVAVFIICWTPIHIFILV 347

  Fly   315 VALIHSNPAQRDLSRLEILIFLLLGALVYSNSAVNPILYAFLSENFRKSF----FKAFTCMNKQD 375
            .||..::.:...||.....|     ||.|:||::||:|||||.|||::.|    |.....|.:|.
  Rat   348 EALGSTSHSTAVLSSYYFCI-----ALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQS 407

  Fly   376 IN 377
            .|
  Rat   408 TN 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R1	NP_649040.2	7tmA_AstC_insect	78..364	CDD:320222	110/289 (38%)
		TM helix 1	79..105	CDD:320222	11/25 (44%)
		TM helix 2	112..138	CDD:320222	13/27 (48%)
		TM helix 3	149..179	CDD:320222	13/29 (45%)
		TM helix 4	191..213	CDD:320222	3/21 (14%)
		TM helix 5	241..270	CDD:320222	7/28 (25%)
		TM helix 6	287..317	CDD:320222	14/31 (45%)
		TM helix 7	332..357	CDD:320222	12/24 (50%)
Oprk1	XP_038965287.1	7tmA_Kappa_opioid_R	111..392	CDD:320219	110/303 (36%)
		TM helix 1	112..138	CDD:320219	11/26 (42%)
		TM helix 2	145..171	CDD:320219	12/25 (48%)
		TM helix 3	182..212	CDD:320219	13/29 (45%)
		TM helix 4	224..246	CDD:320219	3/21 (14%)
		TM helix 5	274..303	CDD:320219	7/28 (25%)
		TM helix 6	318..348	CDD:320219	14/29 (48%)
		TM helix 7	360..385	CDD:320219	14/29 (48%)