Protein Alignment AstC-R1 and tacr1a

DIOPT Version :10

• Sequence 1: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001257407.1
• Gene: tacr1a / 100003539
• ZFINID: ZDB-GENE-060526-185
• Length: 426
• Species: Danio rerio
• Alignment Length: 440
• Identity: 109/440 - (24%)
• Similarity: 191/440 - (43%)
• Gaps: 69/440 - (15%)

  Fly    37 TTELNHRWISGSSTIQPEESLYGTDLPTYQHCIATRNSFAD-LFTVVL----YGFVCIIGLFGNT 96
            :|:....| :.:||.|.|..:|.             |.|.. ::.:||    |..:.::.:.||.
Zfish     7 STDFPSNW-TVNSTAQNETEIYW-------------NQFVQPVWRIVLWAVAYSTIVVVSVVGNI 57

  Fly    97 LVIYVVLRFSKMQTVTNIYILNLAVAD---ECFLIGIPFLLYTMRICSWRFGEFMCKAYMVSTSI 158
            .||:::|...:|:||||.:::|||.|:   ..|...|.| :|::. ..|.||.:.|:.:......
Zfish    58 TVIWIILAHKRMRTVTNYFLVNLAFAEASMSAFNTVINF-VYSVH-NEWYFGLYYCRFHNFFPIA 120

  Fly   159 TSFTSSIFLLIMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVILYASTVEQEDG 223
            ..|.|...:..::.|||:|:.||:......|.  .|||..:.|..:.:|..|...|:.| :|..|
Zfish   121 AVFASIYSMTAIALDRYMAIIHPLQQRMSATQ--TKVVIGVIWILALLLAFPQYYYSDT-DQLPG 182

  Fly   224 INYSCNIMWPDAYKKHSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPKPGTKS---KEK 285
             ...|.|.||:.......|.:.:....|.:..|| .::...|||:.........||..|   :|:
Zfish   183 -RVVCYIDWPEYTLLDFKTMYFVCVAVLIYFLPL-LVMGCAYLVVGLTLWASEIPGDSSDRYQEQ 245

  Fly   286 RRAHRKVTRLVLTVISVYILCWLPHWISQVALIHS-NPAQRDLSRLEILIFLLLGALVYSNSAVN 349
            ..|.|||.::::.|:..:.:||||:.:  ..|||. .|...:.:.:: .::|.:..|..|::..|
Zfish   246 LTAKRKVVKMMIVVVCTFAVCWLPYHV--YFLIHQFYPHLFEHTFIQ-QVYLTIMWLAMSSTMYN 307

  Fly   350 PILYAFLSENFRKSFFKAFTC----------------------------MNKQDINAQLQLEPSV 386
            ||:|..|::.||..|.:||.|                            .::.:.:....::||
Zfish   308 PIIYCCLNDRFRAGFKQAFRCCPCVPEGSYEGLELKSTRYLQTQTSLYRASRMETSVSCVMQPS- 371

  Fly   387 FTKQGSKKRGGSKRLLTSNPQIPPLLPLNAGNNNSSTTTSSTTTAEKTGT 436
              :.|.|...||.|.....|....  |.....:|.|::.|.:.|..:|.:
Zfish   372 --EDGHKVTFGSVRGAAVKPAARS--PSREFTSNGSSSRSISKTVSETSS 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R1	NP_649040.2	7tmA_AstC_insect	78..364	CDD:320222	82/296 (28%)
		TM helix 1	79..105	CDD:320222	8/29 (28%)
		TM helix 2	112..138	CDD:320222	10/28 (36%)
		TM helix 3	149..179	CDD:320222	7/29 (24%)
		TM helix 4	191..213	CDD:320222	6/21 (29%)
		TM helix 5	241..270	CDD:320222	7/28 (25%)
		TM helix 6	287..317	CDD:320222	9/29 (31%)
		TM helix 7	332..357	CDD:320222	7/24 (29%)
tacr1a	NP_001257407.1	7tmA_NK1R	39..322	CDD:320668	82/292 (28%)
		TM helix 1	40..66	CDD:320668	7/25 (28%)
		TM helix 2	73..99	CDD:320668	9/26 (35%)
		TM helix 3	111..141	CDD:320668	7/29 (24%)
		TM helix 4	152..173	CDD:320668	6/22 (27%)
		TM helix 5	199..228	CDD:320668	7/29 (24%)
		TM helix 6	247..277	CDD:320668	10/31 (32%)
		TM helix 7	290..315	CDD:320668	7/25 (28%)