DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstC-R2 and C3ar1

DIOPT Version :9

Sequence 1:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_114449.2 Gene:C3ar1 / 84007 RGDID:620537 Length:472 Species:Rattus norvegicus


Alignment Length:438 Identity:82/438 - (18%)
Similarity:154/438 - (35%) Gaps:156/438 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   146 LITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPF-LLYTMQVGN 209
            :.:|::.:|.|::||.||.||::|. .....:||..::.|:|.:||....:.:|| :.:.:..|:
  Rat    24 IASMVILSLTCLLGLPGNGLVLWVA-GVKMKRTVNTVWFLHLTLADFLCCLSLPFSVAHLILRGH 87

  Fly   210 WPFGNYMCKAYMVSTSITSFTSSIFLL-IMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSV 273
            ||:|.::|| .:.|..|.:..:|:||| .:|.||.:.|..||....:|:...:..|....|:.:.
  Rat    88 WPYGLFLCK-LIPSVIILNMFASVFLLTAISLDRCLMVHKPIWCQNHRSVRTAFAVCGCVWVVAF 151

  Fly   274 LLMLPVILFASTVQSSNGNVSCNIE---------W-------------PDTQNSHTD-------- 308
            ::.:||.::...:...:.:| |...         |             ||....|.|        
  Rat   152 VMCIPVFVYRDLLVVDDYSV-CGYNFDSSRAYDYWDYMYNSHLPEINPPDNSTGHVDDRTAPSSV 215

  Fly   309 --------------STF------------------------------------------------ 311
                          .||                                                
  Rat   216 PARDLWTATTALQSQTFHTSPEDPFSQDSASQQPHYGGKPPTVLIATIPGGFPVEDHKSNTLNTG 280

  Fly   312 ------------------------------ILYS--------------LVLGFATPLTFILVFYC 332
                                          ::|.              ||:||..|...::..|.
  Rat   281 AFLSAHTEPSLTASSSPLYAHDFPDDYFDQLMYGNHAWTPQVAITISRLVVGFLVPFFIMITCYS 345

  Fly   333 LVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELA 397
            |::.::       :.....:|..|..::.:.|::.:..||:|:.|..:.|:.:..:.....:.|.
  Rat   346 LIVFRM-------RKTNLTKSRNKTLRVAVAVVTVFFVCWIPYHIVGILLVITDQESALREVVLP 403

  Fly   398 VFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQ 445
            .......|:.:||..||.|||.|..:|:|.        ||:.|...|:
  Rat   404 WDHMSIALASANSCFNPFLYALLGKDFRKK--------ARQSVKGILE 443

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 59/353 (17%)
7tm_1 162..417 CDD:278431 67/392 (17%)
C3ar1NP_114449.2 7tm_GPCRs 24..434 CDD:421689 78/427 (18%)
TM helix 1 25..51 CDD:410628 10/26 (38%)
TM helix 2 57..82 CDD:410628 6/24 (25%)
TM helix 3 95..125 CDD:410628 11/30 (37%)
TM helix 4 137..157 CDD:410628 2/19 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 232..251 1/18 (6%)
TM helix 5 321..346 CDD:410628 6/24 (25%)
TM helix 6 358..388 CDD:410628 7/29 (24%)
TM helix 7 402..427 CDD:410628 9/24 (38%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X22
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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