Protein Alignment AstC-R2 and gpr83.2

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001072505.1
• Gene: gpr83.2 / 779960
• XenbaseID: XB-GENE-993677
• Length: 420
• Species: Xenopus tropicalis
• Alignment Length: 416
• Identity: 108/416 - (25%)
• Similarity: 192/416 - (46%)
• Gaps: 62/416 - (14%)

  Fly   122 NGSHYLEYDDDGP---DCSY---SYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVT 180
            ||.  |..||.|.   |..|   |.:..:|.:.::.|:::.:|.||||.||.:||::.|:||:.|
 Frog    42 NGD--LNIDDIGDFENDTKYEAESQSSTVKALLIVAYSVIIVISLFGNILVCHVVIKNSRMQSAT 104

  Fly   181 NIYILNLAIADECF-LIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYI 244
            :::|:|||:||... |:..||.|.......|.||..||.........:...|.:.|:.::.||:.
 Frog   105 SLFIVNLAVADIMITLLNTPFTLVRFVSSTWVFGKLMCHVSRFVQYCSVHVSVLTLMAIALDRHQ 169

  Fly   245 AVCHPISSPRYRTPFVSKLVSAFA-WMTSVLLMLPVILFASTVQSSNGN---VSCNIEWP---DT 302
            .:.||: .||..|  |..::.... |..:....||..::....|...||   :.|...:|   |.
 Frog   170 VIMHPL-KPRMST--VKGIICIIVIWFMASGFSLPHAVYQKLEQFFIGNTVRMVCLPSFPYPADL 231

  Fly   303 QNSHTD-STFILYSLVLGFATPLTFILVFYCLVIRKL---HTVGPKHKSKEKKRSHR---KVT-K 359
            ...:.| :||:|.     :..||..|.:.|..|.:||   :.:|  ..:.|:..:||   |:| |
 Frog   232 FWKYLDLATFVLL-----YVLPLIVISITYTTVAKKLWLRNAIG--DITMEQYYAHRRKKKMTLK 289

  Fly   360 LVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNF 424
            :::.|:..:..||.|  ::...::.|:....::.   |::.|....:.|::..||.:|.:|:::|
 Frog   290 MLMLVVVVFAVCWFP--LNCYLVLMSSKVISSNN---AIYFAFHWFAMSSTCYNPFIYCWLNESF 349

  Fly   425 KKSFMKACTCAARKDVNAQLQLENSFFPKFGKGRQSERLLGGNGKGGAQRGALTKKKCLATRNNN 489
             :|.:||..|..|:...||.....|..|:|                   |.|.| :.|...:.::
 Frog   350 -RSELKALLCVCRRRSPAQSHPLQSVSPQF-------------------RHAWT-ENCHFKQGSS 393

  Fly   490 APMATTTTTTTTTTGTDAVTCLQPPV 515
            :..|  .:.|...:|...::.::|.|
 Frog   394 SQAA--GSATNVNSGRTDISSVEPIV 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	79/297 (27%)
		TM helix 1	147..173	CDD:320222	10/25 (40%)
		TM helix 2	180..206	CDD:320222	11/26 (42%)
		TM helix 3	217..247	CDD:320222	5/29 (17%)
		TM helix 4	259..281	CDD:320222	4/22 (18%)
		TM helix 5	308..337	CDD:320222	9/29 (31%)
		TM helix 6	352..382	CDD:320222	9/33 (27%)
		TM helix 7	396..421	CDD:320222	6/24 (25%)
gpr83.2	NP_001072505.1	7tmA_GPR83	70..353	CDD:320511	80/298 (27%)
		TM helix 1	71..97	CDD:320511	10/25 (40%)
		TM helix 2	104..129	CDD:320511	11/24 (46%)
		TM helix 3	142..172	CDD:320511	5/29 (17%)
		TM helix 4	183..204	CDD:320511	3/20 (15%)
		TM helix 5	233..262	CDD:320511	9/33 (27%)
		TM helix 6	282..312	CDD:320511	7/31 (23%)
		TM helix 7	321..346	CDD:320511	6/27 (22%)