Protein Alignment AstC-R2 and SSTR5

DIOPT Version :9

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001044.1
• Gene: SSTR5 / 6755
• HGNCID: 11334
• Length: 364
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 145/372 - (38%)
• Similarity: 201/372 - (54%)
• Gaps: 54/372 - (14%)

  Fly    85 LESVESESYPSIN---------GTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSY 140
            :|.:...|.||.|         |..|.|:|                           ||..|...
Human     1 MEPLFPASTPSWNASSPGAASGGGDNRTLV---------------------------GPAPSAGA 38

  Fly   141 NFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTM 205
            ..:|   ..:||.|||..||.|||||||||:||:||:|||||||||||:||..:::|:|||....
Human    39 RAVL---VPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQN 100

  Fly   206 QVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWM 270
            ....||||..:|:..|....:..|||...|.:||.|||:||.||:||.|:|.|.|:||.||.||:
Human   101 AASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWV 165

  Fly   271 TSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVI 335
            .|:.:.||:::||...:..    :||..||:.... ..:.||:|:.||||..||..|.:.|.|::
Human   166 LSLCMSLPLLVFADVQEGG----TCNASWPEPVGL-WGAVFIIYTAVLGFFAPLLVICLCYLLIV 225

  Fly   336 RKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHW-ISQVALISSAPQRCASRLELAVF 399
            .|:...|.: ....::||.||||::||.|:..:..||||.: ::.|.|..:.||..||   ..::
Human   226 VKVRAAGVR-VGCVRRRSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPAS---AGLY 286

  Fly   400 LACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTC----AARKDVNA 442
            .....|||:||..||:||.||||||::||.|. .|    :..||.:|
Human   287 FFVVILSYANSCANPVLYGFLSDNFRQSFQKV-LCLRKGSGAKDADA 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	96/215 (45%)
		7tm_1	162..417	CDD:278431	110/255 (43%)
SSTR5	NP_001044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/18 (28%)
		7tm_4	54..319	CDD:304433	123/274 (45%)
		7tm_1	57..304	CDD:278431	110/255 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..364		3/6 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I2578
eggNOG	1	0.900	-	-		E33208_3BCR0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000463
OrthoInspector	1	1.000	-	-		mtm8609
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24229
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3938
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.940