Protein Alignment AstC-R2 and SSTR1

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001040.1
• Gene: SSTR1 / 6751
• HGNCID: 11330
• Length: 391
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 145/415 - (34%)
• Similarity: 231/415 - (55%)
• Gaps: 41/415 - (9%)

  Fly    77 PNGTTLHQLESVESESYPSI----NGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCS 137
            ||||.    .|..|...||.    .|..:..........::...|...|||:.     .:|...:
Human     3 PNGTA----SSPSSSPSPSPGSCGEGGGSRGPGAGAADGMEEPGRNASQNGTL-----SEGQGSA 58

  Fly   138 YSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLL 202
            ...:||        |::||::||.||::||||::|::||:|.|||||||||||||..::.:|||:
Human    59 ILISFI--------YSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLV 115

  Fly   203 YTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAF 267
            .:..:.:||||..:|:..:...::..|||...|.::|.|||:||.|||.:.|||.|.|:|:|:..
Human   116 TSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG 180

  Fly   268 AWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYC 332
            .|:.|:|::||:::|:.|..:|:|.|:||:..|:........ |:||:.::||..|:..|.:.|.
Human   181 VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVG-FVLYTFLMGFLLPVGAICLCYV 244

  Fly   333 LVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELA 397
            |:|.|:..|..|...:::|||.||:|.:|:.|:..::.||:|.::.|:..: .|.|..|:..:|:
Human   245 LIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNV-FAEQDDATVSQLS 308

  Fly   398 VFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFFPKFGKGR---- 458
            |.     |.|:||..|||||.|||||||:||.: ..|.:..|..|:..::  ::....|.|
Human   309 VI-----LGYANSCANPILYGFLSDNFKRSFQR-ILCLSWMDNAAEEPVD--YYATALKSRAYSV 365

  Fly   459 ---QSERLLGGNGKGGAQRGALTKK 480
               |.|.|..|   |..:.|..|.:
Human   366 EDFQPENLESG---GVFRNGTCTSR 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	115/281 (41%)
		TM helix 1	147..173	CDD:320222	11/25 (44%)
		TM helix 2	180..206	CDD:320222	16/25 (64%)
		TM helix 3	217..247	CDD:320222	10/29 (34%)
		TM helix 4	259..281	CDD:320222	8/21 (38%)
		TM helix 5	308..337	CDD:320222	10/28 (36%)
		TM helix 6	352..382	CDD:320222	11/29 (38%)
		TM helix 7	396..421	CDD:320222	12/24 (50%)
SSTR1	NP_001040.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		12/50 (24%)
		7tmA_SSTR1	59..334	CDD:320636	117/289 (40%)
		TM helix 1	60..86	CDD:320636	13/33 (39%)
		TM helix 2	93..119	CDD:320636	16/25 (64%)
		TM helix 3	130..160	CDD:320636	10/29 (34%)
		TM helix 4	172..194	CDD:320636	8/21 (38%)
		TM helix 5	220..249	CDD:320636	10/29 (34%)
		TM helix 6	264..294	CDD:320636	11/29 (38%)
		TM helix 7	302..327	CDD:320636	13/29 (45%)