DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and P2ry4

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_113868.1	Gene:	P2ry4 / 63843	RGDID:	61798	Length:	361	Species:	Rattus norvegicus

Alignment Length:	327	Identity:	87/327 - (26%)
Similarity:	156/327 - (47%)	Gaps:	35/327 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNI 182
            |:..:|        || ||.::..|...|:.| .||:|.::||..|...:::.:...:....|..
  Rat    14 PSPSSG--------DG-DCRFNEEFKFILLPM-SYAVVFVLGLALNAPTLWLFLFRLRPWDATAT 68

  Fly   183 YILNLAIADECFLIGIPFLLYTMQVGN-WPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAV 246
            |:.:||::|..:::.:|.|:|.....| ||||..:||..........:.|.:||..:|..||:.:
  Rat    69 YMFHLALSDTLYVLSLPTLVYYYAARNHWPFGTGLCKFVRFLFYWNLYCSVLFLTCISVHRYLGI 133

  Fly   247 CHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNG-NVSCNIEWPDTQNSHTDST 310
            |||:.:.|:..|..:.|:....|:.....::|.:.|.:|  ::|| .:.|:    ||........
  Rat   134 CHPLRAIRWGRPRFASLLCLGVWLVVAGCLVPNLFFVTT--NANGTTILCH----DTTLPEEFDH 192

  Fly   311 FILYS---LVLGFATPLTFILVFYCLVIRKLHTVGP-KHKSKEKKRSHRKVTKLVLTVISAYIFC 371
            ::.:|   :||.|..|....||.|.|:.|:|:...| ..:|..:.||.|.:. :||||   :..|
  Rat   193 YVYFSSAVMVLLFGLPFLITLVCYGLMARRLYRPLPGAGQSSSRLRSLRTIA-VVLTV---FAVC 253

  Fly   372 WLPHWIS-----QVALISSAPQRC-ASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMK 430
            ::|..|:     |..|:.:   .| ...:...|:.....|:.:||.::|:||.|..|.::....:
  Rat   254 FVPFHITRTIYYQARLLQA---DCHVLNIVNVVYKVTRPLASANSCLDPVLYLFTGDKYRNQLQQ 315

  Fly   431 AC 432
            .|
  Rat   316 LC 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	59/221 (27%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	68/266 (26%)
P2ry4	NP_113868.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		2/13 (15%)
		7tmA_P2Y4	32..313	CDD:320496	79/294 (27%)
		TM helix 1	34..58	CDD:320496	7/24 (29%)
		TM helix 2	67..88	CDD:320496	5/20 (25%)
		TM helix 3	105..127	CDD:320496	4/21 (19%)
		TM helix 4	150..166	CDD:320496	2/15 (13%)
		TM helix 5	194..217	CDD:320496	7/22 (32%)
		TM helix 6	240..262	CDD:320496	8/25 (32%)
		TM helix 7	281..306	CDD:320496	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000