Protein Alignment AstC-R2 and BDKRB2

DIOPT Version :9

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_000614.1
• Gene: BDKRB2 / 624
• HGNCID: 1030
• Length: 391
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 90/326 - (27%)
• Similarity: 154/326 - (47%)
• Gaps: 51/326 - (15%)

  Fly   150 ILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQVG-NWPFG 213
            :|:.|..:..:|    |:.|........||..||:.|||.||.....|:||...|:... :|.||
Human    66 VLFVLATLENIF----VLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFG 126

  Fly   214 NYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLP 278
            ..:|:......|:..::|..||:::|.|||:|:...:|..|.|....:||.|...|..::||..|
Human   127 ETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSP 191

  Fly   279 VILFASTVQ-SSNGN--VSCNIEWPDTQNSHTDSTFILYSL-------VLGFATPLTFILVFYCL 333
            :::|.:..: |..|:  .:|.|.:|.          :::.:       |:||..||: ::.|..:
Human   192 MLVFRTMKEYSDEGHNVTACVISYPS----------LIWEVFTNMLLNVVGFLLPLS-VITFCTM 245

  Fly   334 VIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWIS-------QVALISSAPQRCA 391
            .|.::.......|.|| .::.|:.|.|||.|:..:|.||||..||       ::.::||    |.
Human   246 QIMQVLRNNEMQKFKE-IQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSS----CQ 305

  Fly   392 SR------LELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKD--VNAQLQLEN 448
            ..      .::|.|:|     ||||.:||::|..:...|:|...:......:|.  .:..:|:||
Human   306 DERIIDVITQIASFMA-----YSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMEN 365

  Fly   449 S 449
            |
Human   366 S 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	62/226 (27%)
		7tm_1	162..417	CDD:278431	79/278 (28%)
BDKRB2	NP_000614.1	7tmA_BK-2	58..343	CDD:320503	85/301 (28%)
		TM helix 1	60..84	CDD:320503	5/21 (24%)
		TM helix 2	93..114	CDD:320503	10/20 (50%)
		TM helix 3	131..153	CDD:320503	4/21 (19%)
		TM helix 4	176..192	CDD:320503	5/15 (33%)
		TM helix 5	222..245	CDD:320503	6/23 (26%)
		TM helix 6	269..291	CDD:320503	12/21 (57%)
		TM helix 7	311..336	CDD:320503	10/29 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910