DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AstC-R2 and OPRK1

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001305426.1	Gene:	OPRK1 / 4986	HGNCID:	8154	Length:	409	Species:	Homo sapiens

Alignment Length:	291	Identity:	106/291 - (36%)
Similarity:	171/291 - (58%)	Gaps:	5/291 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 LKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQVG 208
            :.:|...:|::|.::||.||:||::|::|::||:|.|||||.|||:||......:||......:.
Human    58 IPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMN 122

  Fly   209 NWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSV 273
            :||||:.:||..:.......|||...|.:||.|||||||||:.:..:|||..:|:::...|:.|.
Human   123 SWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSS 187

  Fly   274 LLMLPVILFAST-VQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRK 337
            .:.:..|:...| |:.....:.|::::||...|..|....:...:..|..|:..|:|.|.|:|.:
Human   188 SVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILR 252

  Fly   338 LHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLP-HWISQVALISSAPQRCASRLELAVFLA 401
            |.:|.....|:||.|:.|::|:|||.|::.::.||.| |....|..:.|.....|:   |:.:..
Human   253 LKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAA---LSSYYF 314

  Fly   402 CGCLSYSNSAMNPILYAFLSDNFKKSFMKAC 432
            |..|.|:||::||||||||.:|||:.|...|
Human   315 CIALGYTNSSLNPILYAFLDENFKRCFRDFC 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	77/216 (36%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	91/256 (36%)
OPRK1	NP_001305426.1	7tm_4	71..>271	CDD:304433	71/199 (36%)
OPRK1	NP_001305426.1	7tm_1	76..330	CDD:278431	91/256 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3681
Isobase	1	0.950	-	0	Normalized mean entropy	S5993
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	6.010