Protein Alignment AstC-R2 and TkR86C

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001097741.1
• Gene: TkR86C / 41286
• FlyBaseID: FBgn0004841
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 141/540 - (26%)
• Similarity: 231/540 - (42%)
• Gaps: 112/540 - (20%)

  Fly    65 SLITPTEQLAVAPNGTTL----HQLES-VESESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGS 124
            |.|..||.|.   |.|.|    .:|.| |.:....|:|.|:..::::|:   :|:|:.....|
  Fly     2 SEIVDTELLV---NCTILAVRRFELNSIVNTTLLGSLNRTEVVSLLSSI---IDNRDNLESIN-- 58

  Fly   125 HYLEYDDDGPDC-------SYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNI 182
               |..|...:|       .|...:..|.|..|::.|:..:.:.||.:|:::|.....|:||||.
  Fly    59 ---EAKDFLTECLFPSPTRPYELPWEQKTIWAIIFGLMMFVAIAGNGIVLWIVTGHRSMRTVTNY 120

  Fly   183 YILNLAIAD------ECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSAD 241
            ::|||:|||      .| :....|:|.:    :||||:..|.......::|..||...|:.:|.|
  Fly   121 FLLNLSIADLLMSSLNC-VFNFIFMLNS----DWPFGSIYCTINNFVANVTVSTSVFTLVAISFD 180

  Fly   242 RYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFAS--TVQSSNG--NVSCNIEWPDT 302
            ||||:.||:.....|...  :::....|..|.:|..|.:|::|  |....||  ...|.:.|||.
  Fly   181 RYIAIVHPLKRRTSRRKV--RIILVLIWALSCVLSAPCLLYSSIMTKHYYNGKSRTVCFMMWPDG 243

  Fly   303 Q--NSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKL---HTVGPK-HKSKEKKRSHRKVTKLV 361
            :  .|..|..:.|..|||.:..|:..:|:.|.|:.|.|   .::|.. .:..|..:|.|||.::.
  Fly   244 RYPTSMADYAYNLIILVLTYGIPMIVMLICYSLMGRVLWGSRSIGENTDRQMESMKSKRKVVRMF 308

  Fly   362 LTVISAYIFCWLPHWI--------SQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYA 418
            :.::|.:..||||:.:        :|||         :::....::|....|:.||:.:||::|.
  Fly   309 IAIVSIFAICWLPYHLFFIYAYHNNQVA---------STKYVQHMYLGFYWLAMSNAMVNPLIYY 364

  Fly   419 FLSDNFKKSFMK--ACTCAARKDVNAQLQLENSFFPKFGKGRQSERLLGGNGKGGAQRGALTKKK 481
            :::..|:..|.:  .|.|..       |.......||       .||...|......||..|...
  Fly   365 WMNKRFRMYFQRIICCCCVG-------LTRHRFDSPK-------SRLTNKNSSNRHTRGGYTVAH 415

  Fly   482 CLATRNNNAPMATTTTTTTTTTGTDAVTCLQPPVHQVPAEIQVGNPATVLVVN-----------A 535
            .|.   |::|     .||.|.....|.|..||            .|.|.|:::           |
  Fly   416 SLP---NSSP-----PTTQTLLAVLAQTLTQP------------KPQTQLLLSHHSPHPTQPSAA 460

  Fly   536 ET-NNCKPPVLHTDLXDRAP 554
            || :..|...:.|.: .:||
  Fly   461 ETKSQWKRSTMETQI-QQAP 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	86/305 (28%)
		TM helix 1	147..173	CDD:320222	7/25 (28%)
		TM helix 2	180..206	CDD:320222	11/31 (35%)
		TM helix 3	217..247	CDD:320222	11/29 (38%)
		TM helix 4	259..281	CDD:320222	4/21 (19%)
		TM helix 5	308..337	CDD:320222	9/28 (32%)
		TM helix 6	352..382	CDD:320222	11/37 (30%)
		TM helix 7	396..421	CDD:320222	7/24 (29%)
TkR86C	NP_001097741.1	7tmA_TACR	84..374	CDD:320512	86/305 (28%)
		TM helix 1	85..111	CDD:320512	7/25 (28%)
		TM helix 2	118..144	CDD:320512	9/26 (35%)
		TM helix 3	156..186	CDD:320512	11/29 (38%)
		TM helix 4	197..218	CDD:320512	4/22 (18%)
		TM helix 5	251..280	CDD:320512	9/28 (32%)
		TM helix 6	299..329	CDD:320512	9/29 (31%)
		TM helix 7	342..367	CDD:320512	7/24 (29%)