DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AstC-R2 and mchr1a

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_001343144.1	Gene:	mchr1a / 353181	ZFINID:	ZDB-GENE-030502-4	Length:	353	Species:	Danio rerio

Alignment Length:	317	Identity:	101/317 - (31%)
Similarity:	167/317 - (52%)	Gaps:	23/317 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 NGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSK---MQTVTNIY 183
            |.|..::.:.|.   .|. |.||..|    :.::|.:|:.||::|:|.:::.:|   .|||.:|:
Zfish    16 NSSKQIQVNTDD---QYG-NAILPSI----FGIICFLGISGNSIVVYTIIKKTKCQAKQTVPDIF 72

  Fly   184 ILNLAIADECFLIGIPFLLYTMQVGN--WPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAV 246
            |.||:|.|..||:|:|||::.: :||  |.||..|||......|.:...|:..|.:|:.|||:|.
Zfish    73 IFNLSIVDLLFLLGMPFLIHQL-LGNGSWCFGATMCKVISALDSNSQTVSTYILTVMTLDRYVAT 136

  Fly   247 CHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTD-ST 310
            .||......||..|:..|.|..|..|::.:.||:::...:...:|.|.|.:..|   |..|: ..
Zfish   137 VHPFRFNHVRTTCVASAVVAAVWALSLISITPVLMYTGLMPLHSGQVGCALLLP---NPSTNICW 198

  Fly   311 FILYSLVLGFATPLTFILVFYCLVIRKLH-TVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLP 374
            |.:|..||.||.|||.|.|.:..:::.:. ||.|.....::.|: :.||::.:.:..|:..||.|
Zfish   199 FTIYQFVLAFALPLTIICVVFFKILKHMSTTVAPLPPRNQQVRT-KSVTRMAVAICLAFFICWAP 262

  Fly   375 HWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKA 431
            ::|.|:..:.......:......|.::.|   |:||.:||.||..||..||:.|:.|
Zfish   263 YYILQIVHLGIQKPSASFYYVYHVAISMG---YANSCINPFLYIILSKTFKRQFIVA 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	73/222 (33%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	83/261 (32%)
mchr1a	XP_001343144.1	7tm_GPCRs	33..313	CDD:333717	94/291 (32%)
		TM helix 1	34..58	CDD:320095	8/27 (30%)
		TM helix 2	70..91	CDD:320095	11/20 (55%)
		TM helix 3	108..130	CDD:320095	5/21 (24%)
		TM helix 4	153..169	CDD:320095	4/15 (27%)
		TM helix 5	197..220	CDD:320095	11/22 (50%)
		TM helix 6	243..268	CDD:320095	7/24 (29%)
		TM helix 7	281..306	CDD:320095	9/27 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010