DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstC-R2 and Gpr183

DIOPT Version :9

Sequence 1:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_898852.2 Gene:Gpr183 / 321019 MGIID:2442034 Length:357 Species:Mus musculus


Alignment Length:306 Identity:77/306 - (25%)
Similarity:149/306 - (48%) Gaps:10/306 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   133 GPDCS-YSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLI 196
            |.:|. |:::...:::..:.|:||.||||.||.|.:.|:::..|....|.:|.:||.|:|..|..
Mouse    14 GNNCDLYAHHSTARVLMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSMNLVISDILFTT 78

  Fly   197 GIPFLLYTMQVG-NWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFV 260
            .:|..:....:| :|..|:.:|:...:...|.::....|:..:|.||:.||.||:...:.:....
Mouse    79 ALPTRIAYYALGFDWRIGDALCRVTALVFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEY 143

  Fly   261 SKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLT 325
            :|.|....|:......||::|  :.:....|:.:..:|:|:.:.:.:....:|.:.:||:..|:|
Mouse   144 AKGVCLSVWILVFAQTLPLLL--TPMSKEEGDKTTCMEYPNFEGTASLPWILLGACLLGYVLPIT 206

  Fly   326 FILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQV-----ALISS 385
            .||:.|..:..||.....::...||...::|....::.:|..:|.|:.|:.::.:     .|.|.
Mouse   207 VILLCYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFILCFTPYHVAIIQHMIKMLCSP 271

  Fly   386 APQRCASRLELAVFL-ACGCLSYSNSAMNPILYAFLSDNFKKSFMK 430
            ....|.:|....:.| ...||...|..|:|.:|.|....:|:..||
Mouse   272 GALECGARHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMK 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 54/216 (25%)
7tm_1 162..417 CDD:278431 62/261 (24%)
Gpr183NP_898852.2 7tmA_EBI2 28..315 CDD:320287 72/288 (25%)
TM helix 1 30..54 CDD:320287 11/23 (48%)
TM helix 2 63..84 CDD:320287 7/20 (35%)
TM helix 3 101..123 CDD:320287 2/21 (10%)
Interaction with G proteins. /evidence=ECO:0000250 122..130 4/7 (57%)
TM helix 4 146..162 CDD:320287 3/15 (20%)
TM helix 5 190..213 CDD:320287 7/22 (32%)
TM helix 6 239..261 CDD:320287 4/21 (19%)
TM helix 7 283..308 CDD:320287 8/24 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 336..357
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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