DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and C5ar2

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_006540120.2	Gene:	C5ar2 / 319430	MGIID:	2442013	Length:	381	Species:	Mus musculus

Alignment Length:	323	Identity:	81/323 - (25%)
Similarity:	149/323 - (46%)	Gaps:	32/323 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 HYLEYDDDGPDCSYSYNF---ILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILN 186
            ||.:..|...||.....|   :..::.::|||.|.::|:.|||||.:|..:.|:.:...: :.|:
Mouse    55 HYSDLPDVPVDCPAGTCFTSDVYLIVLLVLYAAVFLVGVPGNTLVAWVTWKESRHRLGAS-WFLH 118

  Fly   187 LAIADECFLIGIPFLLYTM-QVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPI 250
            |.:||....:.:|||...: |.|:||:|...|......|.::.:.|.:.|..:|.|.::....|.
Mouse   119 LTMADLLCCVSLPFLAVPIAQKGHWPYGAAGCWLLSSITILSMYASVLLLTGLSGDLFLLAFRPS 183

  Fly   251 SSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSS-NGNVSCNIEWPDTQNSHTDSTFILY 314
            ........|..::|.|.:||..:||.:|..::...:|.. ...:.|.|::..:.::....|.:.:
Mouse   184 WKGADHRTFGVRVVQASSWMLGLLLTVPSAVYRRLLQEHYPPRLVCGIDYGGSVSAEVAITTVRF 248

  Fly   315 SLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQ 379
              :.||..||.|:...:.::.|::               .|:...|...|:..:..||.|:.:.:
Mouse   249 --LFGFLGPLVFMAGCHGILQRQM---------------ARRHWPLGTAVVVGFFICWTPYHVLR 296

  Fly   380 VALISSAPQRCASRLELAVFLAC----GCLSYSNSAMNPILYAFLS-DNFKKSFMKACTCAAR 437
            | :|::||..   .|.||..|..    ..|:.::||:|||::.:.. ....||...||..|.|
Mouse   297 V-IIAAAPPH---SLLLARVLEAEPLFNGLALAHSALNPIMFLYFGRKQLCKSLQAACHWALR 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	48/217 (22%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	64/260 (25%)
C5ar2	XP_006540120.2	7tmA_C5aR	79..346	CDD:320242	70/288 (24%)
		TM helix 1	81..105	CDD:320242	11/23 (48%)
		TM helix 2	113..134	CDD:320242	6/21 (29%)
		TM helix 3	151..173	CDD:320242	3/21 (14%)
		TM helix 4	196..212	CDD:320242	6/15 (40%)
		TM helix 5	241..264	CDD:320242	6/24 (25%)
		TM helix 6	272..297	CDD:320242	6/24 (25%)
		TM helix 7	313..338	CDD:320242	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000