DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and Gpr82

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_783600.1	Gene:	Gpr82 / 319200	MGIID:	2441734	Length:	328	Species:	Mus musculus

Alignment Length:	306	Identity:	69/306 - (22%)
Similarity:	138/306 - (45%)	Gaps:	33/306 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 ILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFL-LYTMQVGNWPFG 213
            :.|..:.|||||||:|..:|.:.....:|.|:||:.||..|:......:||: :|.::...|.:.
Mouse    20 VTYIFLFIIGLFGNSLAQWVFLTKIGKKTSTHIYLANLVTANLLVCTAMPFMGIYFLRGFYWKYQ 84

  Fly   214 NYMCKAY----MVSTSITSFTSSIFLLIMSADRYIAVCHPISS----------------PRYRTP 258
            :..|:..    .:|..::.|.|.:.|..::..||..:....|.                .|:|.|
Mouse    85 SVQCRLVNFLGTLSMHVSMFVSLLILSWIAISRYATLMKKESKQEATSCYERMFYGHVLKRFRQP 149

  Fly   259 FVSKLVSAFAWMTSVLLMLPVILFASTVQSS-NGNVSCNIEWPDTQNSHTDSTFILYSLVLGFAT 322
            ..::.:..:.|...:::::||.|:.|.|::: .|...|.....:.....:....::.:..:||:.
Mouse   150 NFARTMCIYIWGVVLVIIIPVTLYYSVVEATEEGQSQCYNRQMELGARPSQIAGLIGTTFIGFSF 214

  Fly   323 PLTFILVFYCLV--IRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISS 385
             |..:..:|.||  :|::.|.   ....||..::|.|.:.:|.:....:.|:||:.|.: .:...
Mouse   215 -LVVVTSYYSLVSHLRRVRTC---TSITEKDLTYRSVKRHLLIIQVLLVVCFLPYSIFK-PIFYV 274

  Fly   386 APQRCASRLELAVFLAC----GCLSYSNSAMNPILYAFLSDNFKKS 427
            ..||.....:|...:..    .||:.:.|:.:||::..|...|||:
Mouse   275 LHQREGDCQQLNYLIEAKNILTCLASARSSTDPIIFLLLDKTFKKT 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	52/239 (22%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	59/282 (21%)
Gpr82	NP_783600.1	7tmA_GPR82	16..321	CDD:320127	69/306 (23%)
		TM helix 1	17..43	CDD:320127	10/22 (45%)
		TM helix 2	50..75	CDD:320127	8/24 (33%)
		TM helix 3	92..122	CDD:320127	6/29 (21%)
		TM helix 4	150..170	CDD:320127	1/19 (5%)
		TM helix 5	199..227	CDD:320127	6/28 (21%)
		TM helix 6	242..272	CDD:320127	7/30 (23%)
		TM helix 7	289..314	CDD:320127	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000