DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and Sstr1

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_036851.1	Gene:	Sstr1 / 25033	RGDID:	3762	Length:	391	Species:	Rattus norvegicus

Alignment Length:	354	Identity:	131/354 - (37%)
Similarity:	211/354 - (59%)	Gaps:	20/354 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 PNGTTLHQLESVESESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYN 141
            ||||......|..|.......|..:....:.....::...|.:.|||:.     .:|...:...:
  Rat     3 PNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTL-----SEGQGSAILIS 62

  Fly   142 FILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQ 206
            ||        |::||::||.||::||||::|::||:|.|||||||||||||..::.:|||:.:..
  Rat    63 FI--------YSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTL 119

  Fly   207 VGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMT 271
            :.:||||..:|:..:...::..|||...|.::|.|||:||.|||.:.|||.|.|:|:|:...|:.
  Rat   120 LRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVL 184

  Fly   272 SVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIR 336
            |:|::||:::|:.|..:|:|.|:||:..|:........ |:||:.::||..|:..|.:.|.|:|.
  Rat   185 SLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVG-FVLYTFLMGFLLPVGAICLCYVLIIA 248

  Fly   337 KLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELAVFLA 401
            |:..|..|...:::|||.||:|.:|:.|:..::.||:|.::.|:..: .|.|..|:..:|:|.
  Rat   249 KMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNV-FAEQDDATVSQLSVI-- 310

  Fly   402 CGCLSYSNSAMNPILYAFLSDNFKKSFMK 430
               |.|:||..|||||.|||||||:||.:
  Rat   311 ---LGYANSCANPILYGFLSDNFKRSFQR 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	88/215 (41%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	101/254 (40%)
Sstr1	NP_036851.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50		10/46 (22%)
		7tm_4	67..>189	CDD:304433	58/121 (48%)
		7tm_1	75..323	CDD:278431	101/254 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I2480
eggNOG	1	0.900	-	-		E33208_3BCR0
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3165
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000463
OrthoInspector	1	1.000	-	-		mtm9091
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.960