Protein Alignment AstC-R2 and npr-26

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001299957.1
• Gene: npr-26 / 24104836
• WormBaseID: WBGene00011372
• Length: 461
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 125/522 - (23%)
• Similarity: 200/522 - (38%)
• Gaps: 130/522 - (24%)

  Fly    68 TPTEQLAVAPNGTTLHQLESVESESY--------PSINGTQNETMVTSVRPHLDHRNRPTQQNGS 124
            ||..|..:......|....|.|.|.|        .|||.|..:                .|.:|.
 Worm    13 TPPPQQPLQQKSLFLKMDASTEFEIYREHYSRVMASINATMCQ----------------EQPDGI 61

  Fly   125 HYLEYDDDGPDCSYS-YNFILK-----LITMILYALVCIIGLFGNTLVIYVV--------MRFSK 175
            .|......||....: |..|.:     ||.::::.|..|:|:.||:.:|.::        .|..:
 Worm    62 LYCPNHTGGPVWVRNVYPPIQELQPKVLIVVVVFVLCFIVGVCGNSSIITIIRGVVEDRRKRMKR 126

  Fly   176 MQTVTNIYILNLAIADECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSA 240
            ......:||..|.:.|....:.:|..:....:|.|.||..|||.:.|..|:....|:..:..||.
 Worm   127 HGDNAILYIGALCVCDFVMSLSLPPAILDSVIGFWIFGTTMCKVHHVFGSVGRIASTFLITAMSF 191

  Fly   241 DRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSV--LLMLPVILFAS----TVQSSNGNVSCNIE- 298
            |||:|||:|   ..:|....:.::|..|.::|:  :|:||::.:||    .:.....:.|.||.
 Worm   192 DRYVAVCYP---HHHRLRSRTFVISTIACLSSIAFVLLLPMLTYASAKEMVLHELKAHESANITR 253

  Fly   299 ----------------WPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKS 347
                            |      .|.:|||     ||:..||..|:.|...:|.||:.    ||
 Worm   254 VRVFKCSDMMPGPIFYW------FTSTTFI-----LGYVVPLILIVYFNLKLINKLYA----HK- 302

  Fly   348 KEKKRSH---RKVTKLVLTVISAYIFCWLPHWISQV-ALISSAPQRCASRLELAVFLACGC---L 405
            :...||.   |:|....:.:.:.|..||.|:|.|.: |:|.|...:..:..|..:| |..|   |
 Worm   303 RVLPRSAIPVRRVVVYTVLIAAVYFVCWTPYWFSVLYAIIMSLLGKPTTNSEWVLF-AIYCVHLL 366

  Fly   406 SYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFFPKFGKGRQSERLLGGNGKG 470
            .|..|:.|.|||..|                    |.|||::|..      |...:.::..||..
 Worm   367 PYFGSSSNWILYGLL--------------------NTQLQMKNDI------GDDGQSIMTTNGVQ 405

  Fly   471 GAQRGALTKKKCLATRNNNAPMATTTTTTTTTTGTDAVTCLQPPVHQVPAEIQVGNPATVLVVNA 535
            ...|.:.::..|.|...::..:.|..|                |:.|..:.:..||..|.:|...
 Worm   406 DLPRRSTSRLICDAGATSSRSIPTNNT----------------PLWQNDSTLTRGNSDTSMVFYQ 454

  Fly   536 ET 537
            :|
 Worm   455 DT 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	86/319 (27%)
		TM helix 1	147..173	CDD:320222	7/33 (21%)
		TM helix 2	180..206	CDD:320222	5/25 (20%)
		TM helix 3	217..247	CDD:320222	11/29 (38%)
		TM helix 4	259..281	CDD:320222	6/23 (26%)
		TM helix 5	308..337	CDD:320222	10/28 (36%)
		TM helix 6	352..382	CDD:320222	10/33 (30%)
		TM helix 7	396..421	CDD:320222	10/27 (37%)
npr-26	NP_001299957.1	7tm_classA_rhodopsin-like	102..382	CDD:410626	82/319 (26%)
		TM helix 2	128..156	CDD:410626	5/27 (19%)
		TM helix 3	168..198	CDD:410626	11/29 (38%)
		TM helix 4	210..229	CDD:410626	5/18 (28%)
		TM helix 5	268..293	CDD:410626	11/35 (31%)
		TM helix 6	313..343	CDD:410626	9/29 (31%)
		TM helix 7	354..382	CDD:410626	12/48 (25%)