DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstC-R2 and FPR3

DIOPT Version :9

Sequence 1:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_002021.3 Gene:FPR3 / 2359 HGNCID:3828 Length:353 Species:Homo sapiens


Alignment Length:312 Identity:83/312 - (26%)
Similarity:156/312 - (50%) Gaps:42/312 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   143 ILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQV 207
            :|.:.:::::.:..:.|:.||.|||:|. .|...:||..|..||||:||..|...:||.:.::.:
Human    24 VLWIFSLLVHGVTFVFGVLGNGLVIWVA-GFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAM 87

  Fly   208 -GNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMT 271
             ..||||:::||...|...|..|.|...:.|::.||.|.|.||..:..:||..::|.|....|:.
Human    88 REKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIF 152

  Fly   272 SVLLMLPVILFASTVQSSNGNVSCNIE---WPDTQNSHTD------STFILYSLVLGFATPLTFI 327
            :::|.||..:|.:|:.::||:..|...   |.||.....:      ..|::...::||:.|::.|
Human   153 TIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSII 217

  Fly   328 LVFYCLVIRKLHTVGPKHKSKEKKRSH----RKVTKLVLTVISAYIFCWLPH---------WISQ 379
            .|.|.::..|:|            |:|    .:..::...|::::..||.|:         |:.:
Human   218 TVCYGIIAAKIH------------RNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKE 270

  Fly   380 VALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKA 431
            :.|...      .::.|.:......|::.||.:|||||.|:..||::..:::
Human   271 MLLNGK------YKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRS 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 65/229 (28%)
7tm_1 162..417 CDD:278431 76/277 (27%)
FPR3NP_002021.3 7tm_GPCRs 27..313 CDD:333717 82/304 (27%)
TM helix 1 29..53 CDD:320095 7/24 (29%)
TM helix 2 61..82 CDD:320095 10/20 (50%)
TM helix 3 99..121 CDD:320095 6/21 (29%)
TM helix 4 144..160 CDD:320095 4/15 (27%)
TM helix 5 199..222 CDD:320095 6/22 (27%)
TM helix 6 237..262 CDD:320095 4/24 (17%)
TM helix 7 281..306 CDD:320095 10/24 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 327..353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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