DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstC-R2 and Sstr1

DIOPT Version :9

Sequence 1:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_033242.1 Gene:Sstr1 / 20605 MGIID:98327 Length:391 Species:Mus musculus


Alignment Length:358 Identity:133/358 - (37%)
Similarity:212/358 - (59%) Gaps:28/358 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 PNGTTLHQLESVESESYPSI----NGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCS 137
            ||||.    .|..|...||.    .|..:....:.....::...|...|||:.     .:|...:
Mouse     3 PNGTA----SSPSSSPSPSPGSCGEGACSRGPGSGAADGMEEPGRNASQNGTL-----SEGQGSA 58

  Fly   138 YSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLL 202
            ...:||        |::||::||.||::||||::|::||:|.|||||||||||||..::.:|||:
Mouse    59 ILISFI--------YSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLV 115

  Fly   203 YTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAF 267
            .:..:.:||||..:|:..:...::..|||...|.::|.|||:||.|||.:.|||.|.|:|:|:..
Mouse   116 TSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG 180

  Fly   268 AWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYC 332
            .|:.|:|::||:::|:.|..:|:|.|:||:..|:........ |:||:.::||..|:..|.:.|.
Mouse   181 VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVG-FVLYTFLMGFLLPVGAICLCYV 244

  Fly   333 LVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELA 397
            |:|.|:..|..|...:::|||.||:|.:|:.|:..::.||:|.::.|:..: .|.|..|:..:|:
Mouse   245 LIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNV-FAEQDDATVSQLS 308

  Fly   398 VFLACGCLSYSNSAMNPILYAFLSDNFKKSFMK 430
            |.     |.|:||..|||||.|||||||:||.:
Mouse   309 VI-----LGYANSCANPILYGFLSDNFKRSFQR 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 88/215 (41%)
7tm_1 162..417 CDD:278431 101/254 (40%)
Sstr1NP_033242.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..50 12/50 (24%)
7tmA_SSTR1 59..334 CDD:320636 117/289 (40%)
TM helix 1 60..86 CDD:320636 13/33 (39%)
TM helix 2 93..119 CDD:320636 16/25 (64%)
TM helix 3 130..160 CDD:320636 10/29 (34%)
TM helix 4 172..194 CDD:320636 8/21 (38%)
TM helix 5 220..249 CDD:320636 10/29 (34%)
TM helix 6 264..294 CDD:320636 11/29 (38%)
TM helix 7 302..327 CDD:320636 13/29 (45%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 224 1.000 Domainoid score I2540
eggNOG 1 0.900 - - E33208_3BCR0
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000463
OrthoInspector 1 1.000 - - mtm8844
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24229
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3938
SonicParanoid 1 1.000 - - X22
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
98.940

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