DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and npr-30

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_001367700.1	Gene:	npr-30 / 186719	WormBaseID:	WBGene00019183	Length:	396	Species:	Caenorhabditis elegans

Alignment Length:	329	Identity:	69/329 - (20%)
Similarity:	125/329 - (37%)	Gaps:	68/329 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 YALVCIIGLFGNTLV---IYVVMRFSKMQTVTN---IYILNLAIADECFLIGIPFLLYTMQVGNW 210
            |..|.:.|..||..|   :.:|..|.|...|..   :.||.:.:||...|:.:...::......|
Worm    25 YITVILFGNIGNVWVSWKVGIVFVFDKSSLVPRNIVMLILFICVADLLVLLHLTLFVHFQFEKQW 89

  Fly   211 PFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAV---CHPISSPRYRT-PFVSKLVSAFAWMT 271
            .|||.:||::.....:......:.||.:|.:.|.:|   .|..|..|... ..|.:|.|..|.:.
Worm    90 IFGNIVCKSFYCIEVVNKLIIPLALLRISRESYESVRMTSHKCSKKRRSIWNIVFQLYSVMALIA 154

  Fly   272 SVLLMLPVILFASTVQ---SSNGNVS----CNIEWPDTQNSHTDS-TFILYSLVLGFATPLTFIL 328
            ..:|.:.|::||.|..   ..:|.::    |....|     |..: .|.:.:.|.|:.......:
Worm   155 VGVLTISVLIFAETRTYEIPRHGELTAVTMCIFHPP-----HPYAMVFNILAFVFGYGFTSAAYM 214

  Fly   329 VFYC---LVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTV---ISAYIFCWLPHW----------- 376
            .||.   :::::.::......|...:.:|:.:.|:..||   :..|:.||.|:|
Worm   215 YFYLRVPMILKRRYSSIKTTSSNSTRFNHQSILKIRHTVNAFVVVYMACWTPYWALFWLFFTFPP 279

  Fly   377 -------ISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTC 434
                   |||:|.:                     |.|.:.|..||:..|::...:.:.....|.
Worm   280 SNNWMVIISQMAHL---------------------LPYISCAAYPIILTFINKGIRNAHSTIMTS 323

  Fly   435 AARK 438
            ..:|
Worm   324 QRKK 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	51/239 (21%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	63/296 (21%)
npr-30	NP_001367700.1	7tm_classA_rhodopsin-like	21..310	CDD:410626	67/310 (22%)
		TM helix 1	21..49	CDD:410626	7/23 (30%)
		TM helix 2	58..81	CDD:410626	5/22 (23%)
		TM helix 3	97..119	CDD:410626	3/21 (14%)
		TM helix 4	140..164	CDD:410626	6/23 (26%)
		TM helix 5	195..218	CDD:410626	4/22 (18%)
		TM helix 6	252..272	CDD:410626	7/19 (37%)
		TM helix 7	285..310	CDD:410626	10/45 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910