DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and F16C3.1

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_492672.1	Gene:	F16C3.1 / 184568	WormBaseID:	WBGene00008885	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	395	Identity:	72/395 - (18%)
Similarity:	131/395 - (33%)	Gaps:	123/395 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 LYALVCIIGLFGNTLVIYVV-MRFSKMQTVTNIYILNLAIADECFLI------------GIPFLL 202
            |..:.|.||:.||::.:.:: ..|...:..:|||:..|::: .||.:            |:|  |
Worm    26 LLPIFCFIGILGNSMALILIRTNFWLRRLTSNIYLCTLSVS-SCFFLLTVIISWADTYMGLP--L 87

  Fly   203 YT-MQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIA---------VCHPISSPRYRT 257
            |: .::|        ||.:......:.|.....:.::|.||.|.         ||....|.....
Worm    88 YSESELG--------CKFFSFLAHFSDFICVWMISLISCDRMIVLYRPRIRKWVCTKKFSRNMTI 144

  Fly   258 PFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQ--NSHTDSTFILYSLV-LG 319
            .||...|..::|     |.|...|....::....|..|.:. .|..  ....|..:.:::|: ..
Worm   145 GFVLSSVVLYSW-----LFLLAGLQIYRLKDGTENTFCGLS-QDVNLFGFQVDQHYFMFTLMDTA 203

  Fly   320 FATPLTFILVF-----------------------------------------------------Y 331
            ..|.|..||:.                                                     |
Worm   204 LCTLLPAILIIIVNSFSTYRYRQCMKIYSSGVLRVRFVRAPTTQQQQQQLNNDTIQFEETTVKKY 268

  Fly   332 CLVIRKLHTVGPKHKSKEK-----KRSHRKVTKLVLTVISAYIFCWLPHWISQV--ALISSAPQR 389
            .|.....|:..|...::.:     :.|..::::.::.|.|.::...:|.:..::  ::|||
Worm   269 LLSTDNTHSNLPTSSTQSRNCGKLRSSDLQLSRTLIIVTSTFVLLNVPSYAMRILQSIISS---- 329

  Fly   390 CASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSF----MKACTCAARKDVNAQLQLENSF 450
             |..|...|:.....:.|.:.|:...:|.|.|...||..    |:...|...|.|
Worm   330 -AGPLFNFVYYVTLLIYYLHHAVLFYMYIFWSPQMKKQLKPTAMRLLECYCLKTV---------- 383

  Fly   451 FPKFG 455
             |.||
Worm   384 -PDFG 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	50/299 (17%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	56/340 (16%)
F16C3.1	NP_492672.1	7tm_classA_rhodopsin-like	26..360	CDD:381740	62/355 (17%)
		TM helix 1	26..47	CDD:381740	6/20 (30%)
		TM helix 2	57..79	CDD:381740	6/22 (27%)
		TM helix 3	96..118	CDD:381740	2/21 (10%)
		TM helix 4	146..162	CDD:381740	6/20 (30%)
		TM helix 5	195..218	CDD:381740	5/22 (23%)
		TM helix 6	297..322	CDD:381740	3/24 (13%)
		TM helix 7	335..360	CDD:381740	5/24 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010