Protein Alignment AstC-R2 and npr-1

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_508816.1
• Gene: npr-1 / 180752
• WormBaseID: WBGene00003807
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 460
• Identity: 108/460 - (23%)
• Similarity: 184/460 - (40%)
• Gaps: 105/460 - (22%)

  Fly   134 PDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECF--LI 196
            ||.|.|...|:..:|  :|..:..:|||||..:|||......:.:|.||:||||| |.:|.  ::
 Worm    17 PDPSQSIYAIVPFLT--VYLFLFFLGLFGNVTLIYVTCSHKALLSVQNIFILNLA-ASDCMMCIL 78

  Fly   197 GIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSP-RYRTPFV 260
            .:|....|....||.|||.:|........|:.|..:..|..::.||||.|..|.|:| ..|..|
 Worm    79 SLPITPITNVYKNWYFGNLLCHLIPCIQGISIFVCTFSLGAIALDRYILVVRPHSTPLSQRGAF- 142

  Fly   261 SKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVS---CNIEWPDTQNSHTDSTFILYSLVLGFAT 322
              |.:...|:.|.::.||.......::.:...:.   |..:|   :::.:...:.:..::..|..
 Worm   143 --LTTVLLWILSFVVTLPYAFNMQMIEYTEERICGYFCTEKW---ESAKSRRAYTMIVMLAQFVV 202

  Fly   323 PLTFILVFYCLV-------------IRKL---------HTVGPKH---------------KSKEK 350
            |  |.::.:|..             |||:         ....|.|               :.|||
 Worm   203 P--FAVMAFCYANIVSVLSKRAQTKIRKMVERTSALESSCAFPSHGLEQYENELNEFLDKQEKEK 265

  Fly   351 KR---SHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQ---RCASR----LELAVFLACGCL 405
            :|   .:|:.|.:::|::..:...||||.:..:.:.....|   |...|    :...:.|....:
 Worm   266 QRVVLQNRRTTSILVTMVVWFGITWLPHNVISLIIEYDDTQSFFRLYGRDDYDISYLLNLFTHSI 330

  Fly   406 SYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFFPKFGKGRQSERL------- 463
            :.||:.:||:|||:|:.:|::..:|.                     .||..|:|:|:
 Worm   331 AMSNNVLNPVLYAWLNPSFRQLVIKT---------------------YFGDRRKSDRIINQTSVY 374

  Fly   464 ----------LGGNGK--GGAQRGALTKKKCLATRNNNAPMATTTTTTTTTTGTDAVTCLQPPVH 516
                      |.|..|  ||....|| |::.|.:.:.|........|.|.|..........|.:.
 Worm   375 KTKIVHDTKHLNGRAKIGGGGSHEAL-KERELNSCSENLSYHVNGHTRTPTPEVQLNEVSSPEIS 438

  Fly   517 QVPAE 521
            ::.||
 Worm   439 KLVAE 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	81/334 (24%)
		TM helix 1	147..173	CDD:320222	10/25 (40%)
		TM helix 2	180..206	CDD:320222	11/27 (41%)
		TM helix 3	217..247	CDD:320222	8/29 (28%)
		TM helix 4	259..281	CDD:320222	6/21 (29%)
		TM helix 5	308..337	CDD:320222	5/41 (12%)
		TM helix 6	352..382	CDD:320222	8/32 (25%)
		TM helix 7	396..421	CDD:320222	8/24 (33%)
npr-1	NP_508816.1	7tmA_NPYR-like	27..351	CDD:320331	81/334 (24%)
		TM helix 1	28..54	CDD:320331	10/27 (37%)
		TM helix 2	61..86	CDD:320331	10/25 (40%)
		TM helix 3	99..129	CDD:320331	8/29 (28%)
		TM helix 4	140..161	CDD:320331	6/23 (26%)
		TM helix 5	188..217	CDD:320331	4/30 (13%)
		TM helix 6	270..300	CDD:320331	7/29 (24%)
		TM helix 7	321..346	CDD:320331	8/24 (33%)