Protein Alignment AstC-R2 and npr-17

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_498743.2
• Gene: npr-17 / 176124
• WormBaseID: WBGene00015559
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 124/534 - (23%)
• Similarity: 198/534 - (37%)
• Gaps: 161/534 - (30%)

  Fly    86 ESVESESYPSINGTQNET----------MVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSY 140
            :|..::|..|.||..:.|          :|..|.|..:|.:
 Worm    11 DSYLNQSMNSENGLDSVTQIMYDMKKYNIVNDVLPPPNHED------------------------ 51

  Fly   141 NFILKLITM-ILYALVCIIGLFGNTLV---IYVVMRFSKMQTVTN--IYILNLAIADECFLIGIP 199
               |.::.| :.|.|:.::|..||..|   ||.|:|.|: .|:.|  ||::.|:..|....:.:|
 Worm    52 ---LHVVIMAVSYLLLFLLGTCGNVAVLTTIYHVIRSSR-ATLDNTLIYVIVLSCVDFGVCLSLP 112

  Fly   200 FLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTP----FV 260
            ..:....:|.|.||...||.:.|..:.....|::.|..||.|||..|||| ...|.|:.    .:
 Worm   113 ITVIDQILGFWMFGKIPCKLHAVFENFGKILSALILTAMSFDRYAGVCHP-QRKRLRSRNFAITI 176

  Fly   261 SKLVSAFAWMTSVLLM-----LPVILFASTVQSSNGNVS------CNIEWPDTQNSHTDSTFILY 314
            ..:::.:|::|...|:     ..:||:|.  :::.|.::      |.::    .:|...:.|.:|
 Worm   177 LLVLAVYAFITLCPLLWSFTAREIILYAK--ETAPGMLTRMKIEKCTVD----IDSQMFTAFTIY 235

  Fly   315 SLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWIS- 378
            ..:|.:.|||..|..||..::.||.......||.:....|  ::...|.|...|..||.|.|::
 Worm   236 QFILCYCTPLVLIAFFYTKLLSKLREHTRTFKSSQIPFLH--ISLYTLAVACFYFLCWTPFWMAT 298

  Fly   379 --QVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVN 441
              .|.|.:||.......:.:.:......|.::|||:|.|||..|                    |
 Worm   299 LFAVYLENSANSSSVPPVFVYIMYFIHALPFTNSAINWILYGAL--------------------N 343

  Fly   442 AQLQLENSFFPKFGKGRQSERLLGGNGKGGAQRGALTKKKCLATRNNNAPMATTTTTTTTTTGTD 506
            .|||             |..|         :.|...|||             |||||.:|.....
 Worm   344 GQLQ-------------QRYR---------SNRSNSTKK-------------TTTTTASTALLEK 373

  Fly   507 AVTCLQPPVHQVPAEIQVGNPATVLVVNAETNNCKPPVLHTDLXDRAPSMPLETV----VFIARR 567
            .:|.|              |..:...||...|:.            |.:.|.:|:    |.:|..
 Worm   374 KITNL--------------NTNSNYQVNGSMNSI------------ATAAPTKTIGNNEVLVATS 412

  Fly   568 XDHQVELDLDTAID 581
            .     :|.|.|.|
 Worm   413 T-----IDDDVATD 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	82/305 (27%)
		TM helix 1	147..173	CDD:320222	10/29 (34%)
		TM helix 2	180..206	CDD:320222	6/27 (22%)
		TM helix 3	217..247	CDD:320222	10/29 (34%)
		TM helix 4	259..281	CDD:320222	3/26 (12%)
		TM helix 5	308..337	CDD:320222	9/28 (32%)
		TM helix 6	352..382	CDD:320222	9/32 (28%)
		TM helix 7	396..421	CDD:320222	8/24 (33%)
npr-17	NP_498743.2	7tm_classA_rhodopsin-like	57..343	CDD:410626	82/315 (26%)
		TM helix 1	57..86	CDD:410626	11/28 (39%)
		TM helix 2	93..118	CDD:410626	5/24 (21%)
		TM helix 3	130..160	CDD:410626	10/29 (34%)
		TM helix 4	172..191	CDD:410626	2/18 (11%)
		TM helix 5	229..254	CDD:410626	9/24 (38%)
		TM helix 6	274..301	CDD:410626	8/28 (29%)
		TM helix 7	318..343	CDD:410626	9/44 (20%)