DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and Ltb4r1

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	NP_032545.1	Gene:	Ltb4r1 / 16995	MGIID:	1309472	Length:	351	Species:	Mus musculus

Alignment Length:	289	Identity:	86/289 - (29%)
Similarity:	153/289 - (52%)	Gaps:	35/289 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 LKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQVG 208
            |.|:.::|.::...:||.||:.|::.:::..:.:|||.:.:||||:||...|:..||.|:.:..|
Mouse    19 LSLLPIVLLSVALAVGLPGNSFVVWSILKRMQKRTVTALLVLNLALADLAVLLTAPFFLHFLARG 83

  Fly   209 NWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSV 273
            .|.|....|:.......|:.:.|.:.:.|||.||.:||..|..|.:.||...::.|.|..|:.|.
Mouse    84 TWSFREMGCRLCHYVCGISMYASVLLITIMSLDRSLAVARPFMSQKVRTKAFARWVLAGIWVVSF 148

  Fly   274 LLMLPVILFASTVQSSNGNVSCNIEWPDTQNS--HTDSTFILYSLVLGFATPLTFILVFYCLVIR 336
            ||.:||::: .||:.:|..:.|...:|:.::.  |     :|:..:.||..|...::..|..:.|
Mouse   149 LLAIPVLVY-RTVKWNNRTLICAPNYPNKEHKVFH-----LLFEAITGFLLPFLAVVASYSDIGR 207

  Fly   337 KLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALI------------SSAPQR 389
            :|       :::..:|| |:..:||:.:|.|:...|||:.:  |.|:            |.|.||
Mouse   208 RL-------QARRFRRS-RRTGRLVVLIILAFAAFWLPYHL--VNLVEAGRTVAGWDKNSPAGQR 262

  Fly   390 CASRLELAVFLACGCLSYSNSAMNPILYA 418
            .  ||...|.:|   |::.:|::||:|||
Mouse   263 L--RLARYVLIA---LAFLSSSVNPVLYA 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	63/217 (29%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	78/268 (29%)
Ltb4r1	NP_032545.1	7tm_1	37..285	CDD:278431	78/268 (29%)
Ltb4r1	NP_032545.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	311..351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000