Protein Alignment AstC-R2 and CX3CR1

DIOPT Version :9

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001164645.1
• Gene: CX3CR1 / 1524
• HGNCID: 2558
• Length: 387
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 86/311 - (27%)
• Similarity: 145/311 - (46%)
• Gaps: 33/311 - (10%)

  Fly   128 EYDDDGPDCSYSYNFIL--KLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIA 190
            ||||....| |..:.::  .:...|.|:::..|||.||.||::.:....|.::||:||:||||::
Human    45 EYDDLAEAC-YIGDIVVFGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALS 108

  Fly   191 DECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRY 255
            |..|:..:||..:.: :......|.|||.......|..|.|..|:.::|.|||:|:....:|...
Human   109 DLLFVATLPFWTHYL-INEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNN 172

  Fly   256 RTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIE-----WPDTQNSHTDSTFILYS 315
            ||......:|...|..::|:..|..:|  |.|..|..:....|     ||..:|..|:
Human   173 RTVQHGVTISLGVWAAAILVAAPQFMF--TKQKENECLGDYPEVLQEIWPVLRNVETN------- 228

  Fly   316 LVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPH----W 376
             .|||..||..:...|..:|:.|.:.        |.....|..||:|.|:..:...|.|:    :
Human   229 -FLGFLLPLLIMSYCYFRIIQTLFSC--------KNHKKAKAIKLILLVVIVFFLFWTPYNVMIF 284

  Fly   377 ISQVALISSAPQRCASRLELAVFLA-CGCLSYSNSAMNPILYAFLSDNFKK 426
            :..:.|....|. |..|.:|.:.|: ...:::|:..:||::|||..:.|::
Human   285 LETLKLYDFFPS-CDMRKDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRR 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	63/220 (29%)
		7tm_1	162..417	CDD:278431	71/264 (27%)
CX3CR1	NP_001164645.1	7tm_1	80..325	CDD:278431	71/264 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910