Protein Alignment AstC-R2 and Grpr

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_032203.1
• Gene: Grpr / 14829
• MGIID: 95836
• Length: 384
• Species: Mus musculus
• Alignment Length: 378
• Identity: 94/378 - (24%)
• Similarity: 161/378 - (42%)
• Gaps: 56/378 - (14%)

  Fly    75 VAPNGTTLHQLESVESESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYS 139
            :|||..: |.  :::.:.:.|.|.|.|:::           :.|...|..|        |...|
Mouse     1 MAPNNCS-HL--NLDVDPFLSCNDTFNQSL-----------SPPKMDNWFH--------PGFIY- 42

  Fly   140 YNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIG-IPFLLY 203
                   :...:|.|:.:|||.||..:|.:......|:.|.|::|.:||:.|...|:. .|....
Mouse    43 -------VIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDAS 100

  Fly   204 TMQVGNWPFGNYMCKAYMVSTSITSFTSSIF-LLIMSADRYIAVCHPISSPRYRTPFVSKLVSAF 267
            ......|.||...|| .:....:||...|:| |..:|||||.|:..|:............|.:|.
Mouse   101 KYLADRWLFGRIGCK-LIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAL 164

  Fly   268 AWMTSVLLMLPVILFAST----VQSSNGN-VSCNIEWPDTQ----NSHTDSTFILYSLVLGFATP 323
            .|:.|:||.:|..:|:..    |:.:|.. :|| ..:|.:.    ..|:.::|:::     :..|
Mouse   165 IWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISC-APYPHSNELHPKIHSMASFLVF-----YVIP 223

  Fly   324 LTFILVFYCLVIR-------KLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVA 381
            |..|.|:|..:.|       .|...|..|..|:.: |.:::.|.||..:..:.|||||:.:..:.
Mouse   224 LAIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIE-SRKRLAKTVLVFVGLFAFCWLPNHVIYLY 287

  Fly   382 LISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTC 434
            ......:...|.|.....:....|:::||.:||.....||.:|:|.|.....|
Mouse   288 RSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLC 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	79/299 (26%)
		TM helix 1	147..173	CDD:320222	8/25 (32%)
		TM helix 2	180..206	CDD:320222	7/26 (27%)
		TM helix 3	217..247	CDD:320222	13/30 (43%)
		TM helix 4	259..281	CDD:320222	7/21 (33%)
		TM helix 5	308..337	CDD:320222	7/35 (20%)
		TM helix 6	352..382	CDD:320222	9/29 (31%)
		TM helix 7	396..421	CDD:320222	5/24 (21%)
Grpr	NP_032203.1	7tmA_GRPR	42..334	CDD:320252	80/307 (26%)
		TM helix 1	43..69	CDD:320252	8/25 (32%)
		TM helix 2	76..102	CDD:320252	7/25 (28%)
		TM helix 3	114..144	CDD:320252	13/30 (43%)
		TM helix 4	156..176	CDD:320252	6/19 (32%)
		TM helix 5	208..233	CDD:320252	7/29 (24%)
		TM helix 6	258..288	CDD:320252	9/30 (30%)
		TM helix 7	302..327	CDD:320252	5/24 (21%)