Protein Alignment AstC-R2 and Ptgdr2

DIOPT Version :9

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_034092.1
• Gene: Ptgdr2 / 14764
• MGIID: 1330275
• Length: 382
• Species: Mus musculus
• Alignment Length: 420
• Identity: 104/420 - (24%)
• Similarity: 172/420 - (40%)
• Gaps: 99/420 - (23%)

  Fly   118 PTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVV---MRFSKMQTV 179
            |...|.|  |.|.|.              ::::|:.|..::||..|.|:::||   ||    |||
Mouse    20 PNHSNSS--LRYIDH--------------VSVLLHGLASLLGLVENGLILFVVGCRMR----QTV 64

  Fly   180 TNIYILNLAIADECFLIGIPFLLYTMQVG-NWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRY 243
            ...::|:||::|......:||..|.:.|| :|..|...||.:.....:..|.|...|..:|.||.
Mouse    65 VTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRC 129

  Fly   244 IAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCN---IEW-----P 300
            :.|..|:.:..:||..|:..|....|..:||..:|..:|..|:...:|.:.|.   :.|     .
Mouse   130 LQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNLLLWNPGPDR 194

  Fly   301 DTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVI 365
            ||...:......:...:|.|..||..|...:..|..:||     |:.::  |:.|.| :||..::
Mouse   195 DTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLRLH-----HRGRQ--RTGRFV-RLVAAIV 251

  Fly   366 SAYIFCWLPHWISQVALISSAPQRCASRLELA----VFLACGCLSYSNSAMNPILYAFLSDNFKK 426
            .|::.||.|:.|  .:|:.:......:..:||    .|:.  .|::.||.:||:||.|
Mouse   252 VAFVLCWGPYHI--FSLLEARAHSVTTLRQLASRGLPFVT--SLAFFNSVVNPLLYVF------- 305

  Fly   427 SFMKACTC-----AARKDVNAQLQ---LENSFFPKFGKGRQSERLLGGNGKGGAQRGALTKKKCL 483
                  ||     ..|:.:.|.|:   :|:|                      .|.|.|
Mouse   306 ------TCPDMLYKLRRSLRAVLESVLVEDS----------------------DQSGGL------ 336

  Fly   484 ATRNNNAPMATTTTTTTTTTGTDAVTCLQP 513
              ||.....::|.|..:|....|.:..|:|
Mouse   337 --RNRRRRASSTATPASTLLLADRIPQLRP 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	62/227 (27%)
		7tm_1	162..417	CDD:278431	73/270 (27%)
Ptgdr2	NP_034092.1	7tm_GPCRs	32..314	CDD:391938	82/324 (25%)
		TM helix 1	34..58	CDD:341315	8/23 (35%)
		TM helix 2	66..87	CDD:341315	6/20 (30%)
		TM helix 3	104..126	CDD:341315	4/21 (19%)
		TM helix 4	149..165	CDD:341315	4/15 (27%)
		TM helix 5	203..226	CDD:341315	5/22 (23%)
		TM helix 6	241..266	CDD:341315	9/27 (33%)
		TM helix 7	282..307	CDD:341315	9/39 (23%)
		Involved in the recycling of CRTH2. /evidence=ECO:0000250	329..332		1/24 (4%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100