DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstC-R2 and Cmklr1

DIOPT Version :9

Sequence 1:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_001345989.1 Gene:Cmklr1 / 14747 MGIID:109603 Length:371 Species:Mus musculus


Alignment Length:334 Identity:92/334 - (27%)
Similarity:157/334 - (47%) Gaps:46/334 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   126 YLEYDDDG-PDCSYSYNF---------------ILKLITMILYALVCIIGLFGNTLVIYVVMRFS 174
            |..|:|.| .|..||..|               :..:..:::|:|||.:||.||.||| |:..|.
Mouse     3 YDAYNDSGIYDDEYSDGFGYFVDLEEASPWEAKVAPVFLVVIYSLVCFLGLLGNGLVI-VIATFK 66

  Fly   175 KMQTVTNIYILNLAIADECFLIGIPF-LLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIM 238
            ..:||..::.:|||:||..|.|.:|. :.|.....:|.||..|||......|...:||...|.::
Mouse    67 MKKTVNTVWFVNLAVADFLFNIFLPMHITYAAMDYHWVFGKAMCKISNFLLSHNMYTSVFLLTVI 131

  Fly   239 SADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSC----NIEW 299
            |.||.|:|..|:.|..:|:..::.:..:..|:.:..|..|.::|..|. :.:|.::|    ::..
Mouse   132 SFDRCISVLLPVWSQNHRSIRLAYMTCSAVWVLAFFLSSPSLVFRDTA-NIHGKITCFNNFSLAA 195

  Fly   300 PDT--QNSHTDSTFILYS---------LVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRS 353
            |::  ..:|:......||         .:.||..|:..|...|..::.||        .:.:...
Mouse   196 PESSPHPAHSQVVSTGYSRHVAVTVTRFLCGFLIPVFIITACYLTIVFKL--------QRNRLAK 252

  Fly   354 HRKVTKLVLTVISAYIFCWLP-HWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILY 417
            ::|..|:::|:|..:..||.| |.:..:.|..:|.......|.|.:..|   ::.:||.||||||
Mouse   253 NKKPFKIIITIIITFFLCWCPYHTLYLLELHHTAVPSSVFSLGLPLATA---VAIANSCMNPILY 314

  Fly   418 AFLSDNFKK 426
            .|:..:|:|
Mouse   315 VFMGHDFRK 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 61/231 (26%)
7tm_1 162..417 CDD:278431 73/271 (27%)
Cmklr1NP_001345989.1 7tmA_CMKLR1 39..325 CDD:320244 84/298 (28%)
TM helix 1 41..65 CDD:320244 12/24 (50%)
TM helix 2 73..94 CDD:320244 8/20 (40%)
TM helix 3 111..133 CDD:320244 5/21 (24%)
TM helix 4 156..172 CDD:320244 2/15 (13%)
TM helix 5 216..239 CDD:320244 4/22 (18%)
TM helix 6 257..279 CDD:320244 7/21 (33%)
TM helix 7 293..318 CDD:320244 12/27 (44%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X22
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.000

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