DRSC/TRiP Functional Genomics Resources

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Protein Alignment AstC-R2 and Ackr3

DIOPT Version :9

Sequence 1:NP_001303398.1 Gene:AstC-R2 / 40019 FlyBaseID:FBgn0036789 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_001258536.1 Gene:Ackr3 / 12778 MGIID:109562 Length:362 Species:Mus musculus


Alignment Length:365 Identity:106/365 - (29%)
Similarity:174/365 - (47%) Gaps:53/365 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 LHQLESVESESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKL 146
            :|..:..|..:|..||...|.:....|    |....||..|.:..|          |:.:||   
Mouse     3 VHLFDYAEPGNYSDINWPCNSSDCIVV----DTVQCPTMPNKNVLL----------YTLSFI--- 50

  Fly   147 ITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIP-FLLYTMQVGNW 210
                 |..:.:||:..|::|::|.::.......|:.|||||||||...:|.|| :::..:|...|
Mouse    51 -----YIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVITIPVWVVSLVQHNQW 110

  Fly   211 PFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLL 275
            |.|...||...:..||..|.|..||..||.|||:::.:...:..|:...|.::|....|:.:..:
Mouse   111 PMGELTCKITHLIFSINLFGSIFFLACMSVDRYLSITYFTGTSSYKKKMVRRVVCILVWLLAFFV 175

  Fly   276 MLPVILFASTVQS-SNGNVSCNIEWPDTQNSHTDSTFI----LYSLVLGFATPLTFILVFYCLVI 335
            .||...:..||.| ||....|...:|:    |:...::    |.|::||||.|.|.|.:||.|:.
Mouse   176 SLPDTYYLKTVTSASNNETYCRSFYPE----HSIKEWLIGMELVSVILGFAVPFTIIAIFYFLLA 236

  Fly   336 RKLHTVG--PKHKSKEKKRSHRKVTKLVLTVISAYIFCWLP-HWISQV---ALISSAPQRCASRL 394
            |.:...|  .||.|:          |::.:.:..::.|||| |::..:   :::...|..|  :|
Mouse   237 RAMSASGDQEKHSSR----------KIIFSYVVVFLVCWLPYHFVVLLDIFSILHYIPFTC--QL 289

  Fly   395 ELAVFLA---CGCLSYSNSAMNPILYAFLSDNFKKSFMKA 431
            |..:|.|   ..|||..:..:||:||:|::.|::...|||
Mouse   290 ENVLFTALHVTQCLSLVHCCVNPVLYSFINRNYRYELMKA 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AstC-R2NP_001303398.1 7tm_4 156..>372 CDD:304433 67/223 (30%)
7tm_1 162..417 CDD:278431 81/269 (30%)
Ackr3NP_001258536.1 7tmA_ACKR3_CXCR7 45..326 CDD:320118 91/304 (30%)
TM helix 1 47..71 CDD:320118 8/31 (26%)
TM helix 2 80..101 CDD:320118 12/20 (60%)
TM helix 3 118..140 CDD:320118 8/21 (38%)
TM helix 4 163..179 CDD:320118 3/15 (20%)
TM helix 5 210..233 CDD:320118 10/22 (45%)
TM helix 6 251..273 CDD:320118 6/31 (19%)
TM helix 7 294..319 CDD:320118 10/24 (42%)
C-terminal cytoplasmic tail. /evidence=ECO:0000250 324..362 3/6 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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