Protein Alignment AstC-R2 and Cckar

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_033957.1
• Gene: Cckar / 12425
• MGIID: 99478
• Length: 436
• Species: Mus musculus
• Alignment Length: 410
• Identity: 95/410 - (23%)
• Similarity: 179/410 - (43%)
• Gaps: 108/410 - (26%)

  Fly    98 GTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFG 162
            |.:|||:....:|      :|:::..|                     .:.::||:.:.::.:.|
Mouse    21 GLENETLFCLDQP------QPSKEWQS---------------------AVQILLYSFIFLLSVLG 58

  Fly   163 NTLVIYVVMRFSKMQTVTNIYILNLAIADECF-LIGIPFLLYTMQVGNWPFGNYMCK--AYMVST 224
            |||||.|::|..:|:|||||::|:||::|... |..:||.|....:.::.||:.:||  .|.:.|
Mouse    59 NTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGT 123

  Fly   225 SITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQ-S 288
            |::  .|:..|:.:|.:||.|:|.|:.|..::|...:..|.|..|..|..:|.|..::::.|. :
Mouse   124 SVS--VSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFT 186

  Fly   289 SNGNVS---CNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLH-----TVGPKH 345
            .|.|.:   |....|......:..||:|  |:| |..|...::|.|.|:..:|:     ....|.
Mouse   187 KNNNQTANMCRFLLPSDAMQQSWQTFLL--LIL-FLIPGVVMVVAYGLISLELYQGIKFDASQKK 248

  Fly   346 KSKEKKRS--------------------------------------------------------- 353
            .:|||:.|
Mouse   249 SAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGRINRIRSSGSAANL 313

  Fly   354 --HRKVTKLVLTVISAYIFCWLPHWISQV--ALISSAPQRCASRLELAVFLACGCLSYSNSAMNP 414
              .::|.::::.::..:..||:|.:.:..  |..:.:.::..|...::..|   .|||::|.:||
Mouse   314 IAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFIL---LLSYTSSCVNP 375

  Fly   415 ILYAFLSDNFKKSFMKACTC 434
            |:|.|::..|:..||....|
Mouse   376 IIYCFMNKRFRLGFMATFPC 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	85/354 (24%)
		TM helix 1	147..173	CDD:320222	9/25 (36%)
		TM helix 2	180..206	CDD:320222	11/26 (42%)
		TM helix 3	217..247	CDD:320222	11/31 (35%)
		TM helix 4	259..281	CDD:320222	6/21 (29%)
		TM helix 5	308..337	CDD:320222	10/28 (36%)
		TM helix 6	352..382	CDD:320222	5/90 (6%)
		TM helix 7	396..421	CDD:320222	10/24 (42%)
Cckar	NP_033957.1	CholecysA-Rec_N	1..47	CDD:462713	7/52 (13%)
		7tm_GPCRs	42..389	CDD:475119	85/354 (24%)
		TM helix 1	44..68	CDD:410628	9/23 (39%)
		TM helix 2	77..99	CDD:410628	9/21 (43%)
		TM helix 3	115..137	CDD:410628	6/23 (26%)
		TM helix 4	160..176	CDD:410628	5/15 (33%)
		TM helix 5	207..230	CDD:410628	8/25 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..280		3/27 (11%)
		TM helix 6	320..342	CDD:410628	3/21 (14%)
		TM helix 7	357..382	CDD:410628	10/27 (37%)