DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and LOC100535160

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_003201711.2	Gene:	LOC100535160 / 100535160	-ID:	-	Length:	351	Species:	Danio rerio

Alignment Length:	360	Identity:	101/360 - (28%)
Similarity:	172/360 - (47%)	Gaps:	57/360 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 QNGSHYLEYDDDGPDCSYSYNFILKLITMILYALV---CIIGLFGNTLVIYVVMRFSKMQTVTNI 182
            :||:...|.....|...| ||.:....|.||.|.:   |..||.||.||:..::|.:| :||.::
Zfish    20 ENGTCANETTAGHPADEY-YNIVHVTETKILPAFIGFLCSTGLVGNVLVLVTILRSAK-KTVPDV 82

  Fly   183 YILNLAIADECFLIGIPFLLYT-MQVGNWPFGNYMCKAYMVSTSITSFTS------SIFLLIMSA 240
            |:.|||:||...:|.:|||::. .:.|:|.||:.:|      |.|||..:      :..:..||.
Zfish    83 YVGNLAVADLVHVIVMPFLIHQWARGGHWVFGSSLC------TIITSLDNCNQVACAAVMTAMSL 141

  Fly   241 DRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIE------- 298
            |||:|:.||......||...:..::.|.|..|.:::||..:.|..::..:|..||::.
Zfish   142 DRYLALVHPFRLLSLRTRSRTIRINLFVWAASFIMVLPAWVHAKVIRFRDGLESCSLNLVSPKQV 206

  Fly   299 -WPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHR------- 355
             |           :.||..|..|..||..||..|.|::  .:|   ....::.|::||
Zfish   207 LW-----------YTLYQTVTSFFLPLPLILTCYILIL--CYT---WRMYRKNKKAHRYNTSLPR 255

  Fly   356 ----KVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPIL 416
                ::||:||.:::.::....|:.|.|  |::.:..|.:.......:|:. ||||:.|::||.:
Zfish   256 ERVVRLTKMVLVLVAVFLVSVGPYHILQ--LVNLSVPRPSLAYHTCYYLSV-CLSYAASSINPFI 317

  Fly   417 YAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFF 451
            |..||.:|:...:...| .:...|..::|...|.|
Zfish   318 YILLSGHFRHRLVCRDT-PSMPSVEREIQAPRSSF 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	68/241 (28%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	78/280 (28%)
LOC100535160	XP_003201711.2	7tmA_MCHR2	47..329	CDD:320461	88/307 (29%)
		TM helix 1	48..74	CDD:320461	10/25 (40%)
		TM helix 2	80..106	CDD:320461	10/25 (40%)
		TM helix 3	118..148	CDD:320461	11/35 (31%)
		TM helix 4	160..180	CDD:320461	4/19 (21%)
		TM helix 5	206..235	CDD:320461	11/41 (27%)
		TM helix 6	256..286	CDD:320461	8/31 (26%)
		TM helix 7	297..322	CDD:320461	9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100