Protein Alignment AstC-R2 and brs3

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_002932668.2
• Gene: brs3 / 100488712
• XenbaseID: XB-GENE-960289
• Length: 402
• Species: Xenopus tropicalis
• Alignment Length: 372
• Identity: 108/372 - (29%)
• Similarity: 179/372 - (48%)
• Gaps: 38/372 - (10%)

  Fly    91 ESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALV 155
            |.|.::|.|.:.  ||....||..      .|||..| |.::..|.|.... :|..|: |.||::
 Frog     3 EGYLNLNETLSS--VTKNTAHLRF------SNGSDAL-YQEESADLSPRLE-VLATIS-ITYAVI 56

  Fly   156 CIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIG-IPFLLYTMQVGNWPFGNYMCKA 219
            ..:||.|||::|.|..:...||||.||:|.:||..|...|:. :|.......|..|.||...||
 Frog    57 ISVGLLGNTILIKVFFKVKSMQTVPNIFITSLAFGDLLLLLTCVPVDASRYMVDTWLFGRMGCK- 120

  Fly   220 YMVSTSITSFTSSIF-LLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFA 283
            .:....:||...|:| |.::|||||.|:..|:..........:...:|..|:.|:||..|..:|:
 Frog   121 ILSFIQLTSVGVSVFTLTVLSADRYRAIVKPLELQTSDAVLKTCGKAACVWIISMLLAAPEAVFS 185

  Fly   284 STVQSSNGNVSCNIE----WPDT----QNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLH- 339
            ...:.|:.:.:.:.:    :|.:    |.:|:...|:::.:|     ||:.|..:|.|:.:.|:
 Frog   186 DLYEFSSPDKNTSFKACAPYPVSEKLMQETHSLMCFLVFYIV-----PLSIISAYYILIAKTLYK 245

  Fly   340 ----TVGPKHKSKEKK-RSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCA---SRLEL 396
                ....:|....|: .|.::|.|.||.:::.:.|||||:.|  :.|..|.....|   |.|.|
 Frog   246 STFNMPAEEHTHARKQIESRKRVAKTVLVLVALFAFCWLPNHI--LYLYRSFTYHSAVNSSMLHL 308

  Fly   397 AVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQ 443
            :..:....|::|||.:||....:||.:|::.|.|...|...:.:.:|
 Frog   309 SATIFARILAFSNSCVNPFALYWLSRSFRQHFKKQVYCCPEQPLQSQ 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	88/300 (29%)
		TM helix 1	147..173	CDD:320222	11/25 (44%)
		TM helix 2	180..206	CDD:320222	8/26 (31%)
		TM helix 3	217..247	CDD:320222	13/30 (43%)
		TM helix 4	259..281	CDD:320222	6/21 (29%)
		TM helix 5	308..337	CDD:320222	7/28 (25%)
		TM helix 6	352..382	CDD:320222	11/29 (38%)
		TM helix 7	396..421	CDD:320222	7/24 (29%)
brs3	XP_002932668.2	7tm_GPCRs	47..340	CDD:475119	88/301 (29%)
		TM helix 1	49..73	CDD:410628	11/24 (46%)
		TM helix 2	82..104	CDD:410628	8/21 (38%)
		TM helix 3	120..142	CDD:410628	6/22 (27%)
		TM helix 4	165..181	CDD:410628	5/15 (33%)
		TM helix 5	214..237	CDD:410628	6/27 (22%)
		TM helix 6	269..291	CDD:410628	9/23 (39%)
		TM helix 7	308..333	CDD:410628	7/24 (29%)