DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AstC-R2 and npbwr1

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_031750555.1	Gene:	npbwr1 / 100487226	XenbaseID:	XB-GENE-984596	Length:	329	Species:	Xenopus tropicalis

Alignment Length:	323	Identity:	110/323 - (34%)
Similarity:	183/323 - (56%)	Gaps:	20/323 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 HRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQT 178
            |.|  |..:||     .:..||        ..::..|:||::|::||.|||.||||:::..||:|
Frog    22 HAN--TSHHGS-----SEMSPD--------FYIVLPIIYAIICVVGLTGNTAVIYVILKAPKMKT 71

  Fly   179 VTNIYILNLAIADECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRY 243
            |||::||||||||:.|.:.:|..:..:.:..||||..:||..:.......|:|..||.:||.|||
Frog    72 VTNLFILNLAIADDLFTLVLPINIAEILLHYWPFGVVLCKVILSIDLYNIFSSIYFLTVMSIDRY 136

  Fly   244 IAVCHPISSPR--YRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSH 306
            :.|...:.|.|  |||...:|::|...|:..::::||..:||..........||.:.:|..:...
Frog   137 LVVLATVRSKRMPYRTYRAAKVISLLVWLLVIIIVLPFTIFAGVYMDDMDFKSCGLNFPKPEKLW 201

  Fly   307 TDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFC 371
            ..::.| |:|:||||.|::.|.|.|.:::.||..:.....:|...::.::||.:|..|::..:||
Frog   202 FKASRI-YTLLLGFAIPVSTICVLYMVMLYKLRNMRLNSNAKALDKAKKRVTVMVFVVVAVCLFC 265

  Fly   372 WLPHWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTC 434
            |.|..::.:..:::..|..:..:.::.|:.  .|||:||.:||.|||||.|:|:|||.|...|
Frog   266 WTPFHLATIVSLTTDLQETSLVIGISYFIT--SLSYANSCLNPFLYAFLDDSFRKSFRKLLEC 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	76/217 (35%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	85/256 (33%)
npbwr1	XP_031750555.1	7tmA_NPBWR	39..320	CDD:320215	99/283 (35%)
		TM helix 1	41..65	CDD:320215	13/23 (57%)
		TM helix 2	74..95	CDD:320215	11/20 (55%)
		TM helix 3	111..133	CDD:320215	6/21 (29%)
		TM helix 4	158..174	CDD:320215	3/15 (20%)
		TM helix 5	203..226	CDD:320215	10/23 (43%)
		TM helix 6	252..274	CDD:320215	7/21 (33%)
		TM helix 7	288..313	CDD:320215	12/26 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000