DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AstC-R2 and ccr7

DIOPT Version :9

Sequence 1:	NP_001303398.1	Gene:	AstC-R2 / 40019	FlyBaseID:	FBgn0036789	Length:	593	Species:	Drosophila melanogaster
Sequence 2:	XP_004918750.1	Gene:	ccr7 / 100485139	XenbaseID:	XB-GENE-490572	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	366	Identity:	103/366 - (28%)
Similarity:	168/366 - (45%)	Gaps:	74/366 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 LYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQVG-NWPFGN 214
            :||:|.::||.||.||:...:.|::::|.|:.|:|||||||..||:.:||  :.:.|. .|.|||
Frog    65 MYAIVGLVGLAGNGLVMVRYLYFNRLKTGTDYYMLNLAIADIVFLLTLPF--WAVSVAKTWIFGN 127

  Fly   215 YMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYR--TPFVSKLVSAFAWMTSVLLML 277
            .|||.......::.|:....|:.:|.:||.|:....|:.|:|  |..:|||.|...|:.:.||.:
Frog   128 EMCKIIYCLYKMSFFSGMFLLMCVSMERYFAIVQAPSAHRHRSKTVLISKLSSLGIWVFAFLLSI 192

  Fly   278 PVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVG 342
            |.:|::..  ..|..|...|.:.|:..|.| :...:..:..||..||..::..||::||||
Frog   193 PELLYSGV--KENAKVDMCIIFSDSIQSLT-AKLKISQMFFGFFLPLLIMVSCYCMIIRKL---- 250

  Fly   343 PKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALIS--SAPQRC--ASRLELA----VF 399
            .:.::.||    .|..|:::.::..::...||:  :.|.||.  |....|  :..|::|    ..
Frog   251 LQARNFEK----YKAIKVIIAIVIVFVAFQLPY--NSVMLIRAFSNSTECDTSKNLDIADDVTYS 309

  Fly   400 LACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFFPKFGKGRQSERLL 464
            |||     ....:||.|||.:...|:....|..     ||:
Frog   310 LAC-----FRCCLNPFLYAIIGIKFRNDLYKLF-----KDI------------------------ 340

  Fly   465 GGNGKGGAQRGALTKKKC----LATRNNNAPMATTTTTTTT 501
                      |.|:::||    .|..:....:|..|.||||
Frog   341 ----------GCLSQEKCSEWSSAKPSKRTSLAMDTETTTT 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tm_4	156..>372	CDD:304433	68/218 (31%)
AstC-R2	NP_001303398.1	7tm_1	162..417	CDD:278431	80/265 (30%)
ccr7	XP_004918750.1	7tmA_CCR7	60..333	CDD:341331	89/287 (31%)
		TM helix 1	60..87	CDD:341331	9/21 (43%)
		TM helix 2	94..119	CDD:341331	13/26 (50%)
		TM helix 3	130..160	CDD:341331	8/29 (28%)
		TM helix 4	174..196	CDD:341331	8/21 (38%)
		TM helix 5	220..249	CDD:341331	8/29 (28%)
		TM helix 6	256..286	CDD:341331	8/35 (23%)
		TM helix 7	301..326	CDD:341331	9/29 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000