Protein Alignment AstC-R2 and sstr2a

DIOPT Version :10

• Sequence 1: NP_001303398.1
• Gene: AstC-R2 / 40019
• FlyBaseID: FBgn0036789
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: XP_005170178.1
• Gene: sstr2a / 100333578
• ZFINID: ZDB-GENE-140130-1
• Length: 379
• Species: Danio rerio
• Alignment Length: 319
• Identity: 123/319 - (38%)
• Similarity: 192/319 - (60%)
• Gaps: 22/319 - (6%)

  Fly   122 NGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILN 186
            ||:|        |...::.:.::..:    |.:||.:||.||.|||||::|::||:|||||||||
Zfish    39 NGTH--------PGFDHTSSVVITFV----YFVVCAVGLCGNALVIYVILRYAKMKTVTNIYILN 91

  Fly   187 LAIADECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPIS 251
            ||:||...::.:||:...:.:.:||||:.:|:..:...|:..|||..||.:||.|||:||.|||.
Zfish    92 LAVADVLCMLSLPFIAIQLSLLHWPFGSAICRVVLTVDSMNQFTSIFFLTVMSFDRYLAVVHPIK 156

  Fly   252 SPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNGNVSCNIEWPDTQNSHTDSTFILYSL 316
            |.::|.|.::|.:|...|..::|:.||:::::......|...:|.:.||:.||::. :.||.|:.
Zfish   157 STKWRKPRMAKTISLGMWSVALLVNLPIMIYSGVNAKKNEARTCTMLWPEPQNTYY-TAFIFYTF 220

  Fly   317 VLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVA 381
            .|||..||..|.:.|.|::.|:.:.|.:..|.::|||.||||::|..|:..::.||||.::..|.
Zfish   221 FLGFFLPLIVISMCYLLIVIKVKSSGMRVGSTKRKRSERKVTRMVSIVVVVFVLCWLPFYVFNVT 285

  Fly   382 LIS-SAPQR--CASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAAR 437
            .:: :.|..  ..|..:..|     .|.|:||..||||||||||||||||... .|..|
Zfish   286 SVTGTVPTTPVLKSTFDFVV-----VLGYANSCANPILYAFLSDNFKKSFQNV-LCLKR 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AstC-R2	NP_001303398.1	7tmA_AstC_insect	146..428	CDD:320222	115/284 (40%)
		TM helix 1	147..173	CDD:320222	12/25 (48%)
		TM helix 2	180..206	CDD:320222	13/25 (52%)
		TM helix 3	217..247	CDD:320222	13/29 (45%)
		TM helix 4	259..281	CDD:320222	6/21 (29%)
		TM helix 5	308..337	CDD:320222	11/28 (39%)
		TM helix 6	352..382	CDD:320222	13/29 (45%)
		TM helix 7	396..421	CDD:320222	12/24 (50%)
sstr2a	XP_005170178.1	7tm_GPCRs	51..330	CDD:475119	115/288 (40%)
		TM helix 1	53..77	CDD:320637	12/27 (44%)
		TM helix 2	86..107	CDD:320637	12/20 (60%)
		TM helix 3	123..145	CDD:320637	7/21 (33%)
		TM helix 4	168..184	CDD:320637	4/15 (27%)
		TM helix 5	213..236	CDD:320637	9/22 (41%)
		TM helix 6	262..284	CDD:320637	7/21 (33%)
		TM helix 7	298..323	CDD:320637	13/29 (45%)